Augmentin 625mg Tablets Gsk x 14

Augmentin 625mg is a powerful antibiotic medication combining amoxicillin with clavulanic acid. This formulation effectively treats bacterial infections by overcoming resistance mechanisms while providing broad-spectrum coverage against common pathogenic bacteria.

Uses

Augmentin 625mg Tablets treat various bacterial infections including respiratory tract infections, urinary tract infections, typhoid fever, skin and soft tissue infections, dental infections, bone and joint infections, and intra-abdominal infections. It’s particularly effective against infections caused by beta-lactamase-producing bacteria resistant to amoxicillin alone.

Benefits

• Provides broad-spectrum antibacterial activity
• Overcomes bacterial resistance mechanisms
• Offers dual-action infection fighting
• Shows rapid therapeutic response
• Augmentin 625mg ensures reliable effectiveness
• Features convenient dosing schedule
• Demonstrates proven clinical efficacy
• Suitable for various infection types
• Maintains consistent drug levels
• Works against resistant bacteria

How It Works

Augmentin 625mg works through a dual mechanism. Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Clavulanic acid inactivates beta-lactamase enzymes that would otherwise destroy amoxicillin, protecting the antibiotic from bacterial resistance mechanisms and extending its spectrum of activity.

Duration of Action

The active components reach peak plasma concentrations within 1-2 hours after oral administration. Therapeutic concentrations typically remain in the bloodstream for 8-12 hours, supporting the twice-daily dosing regimen.

Dosage

Warnings

Hypersensitivity reactions including anaphylaxis can occur and may be life-threatening. Discontinue immediately if rash or other allergic reactions develop. Not suitable for patients with penicillin allergy, mononucleosis, or severe liver impairment. Prolonged use may result in superinfection.

Side Effects

Common side effects include diarrhea, nausea, vomiting, and skin rash. Less common effects include antibiotic-associated colitis, liver function abnormalities, headache, dizziness, and candidiasis. Rare but serious side effects include Stevens-Johnson syndrome and toxic epidermal necrolysis.

Pregnancy and Breastfeeding

Augmentin 625mg can be used during pregnancy when clearly needed. It passes into breast milk in small amounts but is generally considered compatible with breastfeeding. Consult healthcare provider before use during pregnancy or breastfeeding.

Interactions

• Oral contraceptives (reduced effectiveness)
• Allopurinol (increased risk of skin rash)
• Anticoagulants (increased bleeding risk)
• Methotrexate (increased toxicity)
• Probenecid (increased amoxicillin levels)
• Mycophenolate mofetil (reduced effectiveness)
• Live vaccines (potentially reduced efficacy)

Precautions

Take Augmentin 625mg at the start of a meal to enhance absorption and reduce gastrointestinal effects. Complete the full prescribed course even if symptoms improve earlier. Store tablets in a cool, dry place away from direct sunlight. If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose.

Important Information

Augmentin 625mg Tablets are effective only against bacterial infections, not viral infections such as cold or flu. Unnecessary use increases the risk of developing antibiotic resistance. Monitor for signs of liver problems including yellowing of skin or eyes, dark urine, or pale stools.