Name: Colchicine 1mg Opocalcium Tablet x20
SKU: COL7364
Price: 10000 NGN
Availability: InStock

Colchicine 1mg Opocalcium Tablet is a potent medication primarily used to treat and prevent gout attacks. It’s also effective in managing Familial Mediterranean Fever (FMF), a hereditary inflammatory disorder.

Uses

Colchicine 1mg is used to treat acute gout attacks, prevent recurrent gout flares, and manage symptoms of Familial Mediterranean Fever. It may also be prescribed for other inflammatory conditions in some cases.

Benefits

Effectively relieves pain and inflammation in acute gout attacks
Helps prevent recurrent gout flares when used prophylactically
Reduces frequency and severity of FMF episodes
Can be used in combination with other gout treatments
Provides rapid relief when taken at the first sign of a gout attack
Well-established safety profile when used as directed

How It Works

Colchicine works by reducing inflammation in the body. It interferes with the function of white blood cells (neutrophils) that contribute to the inflammatory process, thereby reducing pain and swelling associated with gout and FMF.

Dosage

For acute gout attacks, the typical dosage is 1mg initially, followed by 0.5mg an hour later. For gout prevention, the usual dose is 0.5-1mg daily. Dosage for FMF varies. Always follow your doctor’s prescription precisely.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, and abdominal pain. If severe side effects occur, such as muscle weakness or unusual bleeding, seek immediate medical attention.

Warning

Colchicine can be toxic if taken in high doses. Never exceed the prescribed dose. Patients with kidney or liver disease may need dose adjustments. Colchicine can interact with many medications, potentially leading to serious side effects.

Pregnancy and Breastfeeding

Colchicine 1mg should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor if you are pregnant or planning to become pregnant. Colchicine is excreted in breast milk and may affect nursing infants.

Interaction

May interact with certain antibiotics, increasing colchicine toxicity
Potential interactions with statins, increasing the risk of muscle problems
Can interact with grapefruit juice, enhancing its effects and side effects

Important Information

Take Colchicine exactly as prescribed. Do not stop taking this medication without consulting your doctor. Inform all healthcare providers that you are taking Colchicine before any surgery or medical treatment. Avoid consuming grapefruit or grapefruit juice while taking this medication. If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. In that case, skip the missed dose. Never take a double dose to make up for a missed one.

Category	Dosage Instructions
Adults (Acute Gout Flare)	Start with 1 tablet (1 mg) initially, followed by 0.5 mg (half tablet) every 1-2 hours until pain relief is achieved, or a maximum dose of 6 mg in 24 hours, whichever comes first. Do not repeat the course for at least 3 days.
Adults (Gout Prophylaxis)	0.5 mg (half tablet) to 1 mg (1 tablet) once or twice daily, depending on response and tolerance. Maximum: 2 mg per day.
Adults (Familial Mediterranean Fever)	1-2 mg daily in divided doses. Adjust according to response and tolerance. Maximum: 3 mg per day.
Elderly Patients (>70 years)	Start with a lower dose (0.5 mg once daily) and adjust based on clinical response and tolerance.
Patients with Renal or Hepatic Impairment	Reduce dosage or increase dosing interval. Consult a healthcare provider for specific dosing instructions.
Maximum Daily Dose	Do not exceed 6 mg in 24 hours for acute gout flare; for other conditions, do not exceed the recommended daily dose.
Administration Instructions	Take orally, with a full glass of water. May be taken with or without food to reduce stomach upset.
Missed Dose	If a dose is missed, take it as soon as remembered unless it is almost time for the next dose; do not double the dose.

Important Notes:

Indications: Used primarily for the treatment and prevention of gout flares and for familial Mediterranean fever.
Side Effects: Common side effects may include nausea, vomiting, diarrhea, and abdominal pain. Severe side effects may include muscle weakness, numbness, tingling, or severe gastrointestinal symptoms. If any severe side effects occur, discontinue use and seek medical advice.
Pregnancy and Breastfeeding: Not recommended during pregnancy or breastfeeding unless clearly needed. Consult a healthcare provider before use.
Interactions: May interact with statins, antifungals, antibiotics, and other medications that affect liver enzymes. Inform your doctor of all medications and supplements being taken.
Special Precautions: Caution in patients with renal or hepatic impairment, elderly patients, or those with gastrointestinal, cardiovascular, or hematologic disorders.
Storage Instructions: Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.