Daonil, with its active ingredient Glibenclamide, is a widely prescribed oral medication for managing type 2 diabetes. This sulfonylurea drug plays a crucial role in blood glucose control by stimulating insulin production in the pancreas. Daonil is valued for its efficacy in lowering blood sugar levels, making it an essential component of diabetes management for many patients.
Uses
Daonil is primarily used for:
- Treatment of type 2 diabetes mellitus
- Lowering blood glucose levels in patients who cannot achieve adequate control through diet and exercise alone
Benefits
- Effective reduction of blood glucose levels
- Improved insulin production by the pancreas
- Helps prevent diabetes-related complications
- Convenient oral administration
- Can be used in combination with other diabetes medications
Mechanism of Action
Daonil works through several mechanisms:
- Stimulates insulin release from pancreatic beta cells
- Increases sensitivity of peripheral tissues to insulin
- Reduces glucose production in the liver
- Enhances glucose uptake and utilization in muscle and fat tissues
Dosage
The dosage of Daonil varies based on individual patient needs and should be determined by a healthcare provider. Generally:
- Starting dose: 2.5 to 5 mg once daily with breakfast or first main meal
- Maintenance dose: May be adjusted up to a maximum of 15 mg daily, taken in divided doses
- Dose adjustments should be made based on regular blood glucose monitoring
Warning
- Risk of hypoglycemia (low blood sugar), especially when skipping meals or engaging in unusual physical activity
- May cause weight gain
- Can interact with other medications, including some antibiotics and blood thinners
- Not suitable for patients with type 1 diabetes or diabetic ketoacidosis
Important Information
- Regular blood glucose monitoring is essential
- Inform healthcare providers about all current medications and medical conditions
- Maintain a consistent diet and exercise routine while taking Daonil
- Avoid alcohol consumption, as it can increase the risk of hypoglycemia
- Seek immediate medical attention if experiencing symptoms of severe hypoglycemia
- Not recommended during pregnancy or breastfeeding without careful medical supervision
- Store at room temperature, away from moisture and heat
- Do not use after the expiration date
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