Crescents Simvastatin 20mg Tablet x28

Crescents Simvastatin 20mg is a potent statin medication designed to effectively manage cholesterol levels. This prescription drug contains simvastatin as its active ingredient, offering a reliable solution for patients requiring lipid control and cardiovascular risk reduction.

Uses

• Primary prevention of cardiovascular events in high-risk patients
• Secondary prevention in patients with coronary heart disease
• Treatment of primary hypercholesterolemia and mixed dyslipidemia
• Management of heterozygous familial hypercholesterolemia in pediatric patients
• Slowing the progression of atherosclerosis

Benefits

• Significantly reduces LDL (bad) cholesterol levels
• Moderately increases HDL (good) cholesterol
• Lowers triglyceride levels effectively
• Decreases risk of heart attack, stroke, and cardiovascular death
• Improves overall lipid profile comprehensively
• Provides cost-effective cholesterol management treatment
• Reduces long-term cardiovascular complications
• Well-established safety and efficacy profile
• Available in convenient once-daily dosing

How It Works

Crescents Simvastatin 20mg works by inhibiting HMG-CoA reductase, a key enzyme in liver cholesterol synthesis. This action increases LDL receptor activity, enhancing LDL cholesterol clearance from the bloodstream while modestly increasing HDL cholesterol and reducing triglycerides.

Dosage

Take Crescents Simvastatin 20mg once daily in the evening with or without food. Dosage adjustments based on lipid levels and treatment goals.

Duration of Action

Crescents Simvastatin 20mg begins working within hours of administration, with peak plasma concentrations reached in 1-2 hours. Cholesterol reduction typically becomes evident within 2 weeks, with maximum effects achieved after 4-6 weeks of consistent therapy.

Side Effects

Common side effects include muscle pain, headache, and gastrointestinal discomfort. Rare but serious effects include myopathy, rhabdomyolysis, and liver dysfunction. Most patients tolerate Crescents Simvastatin 20mg well with regular monitoring.

Warning

Use Crescents Simvastatin 20mg with caution in patients with liver disease history, heavy alcohol use, or myopathy risk. Contraindicated during pregnancy and lactation. Patients should promptly report unexplained muscle pain, tenderness, or weakness to healthcare providers.

Pregnancy and Breastfeeding

Crescents Simvastatin 20mg is contraindicated during pregnancy due to potential fetal harm from cholesterol synthesis inhibition. Women of childbearing age should use effective contraception. The medication is also contraindicated during breastfeeding as it may pass into breast milk.

Interaction

• Increased myopathy risk with gemfibrozil and other fibrates
• Enhanced cholesterol-lowering effect when combined with ezetimibe
• Potential interaction with strong CYP3A4 inhibitors like itraconazole
• Increased myopathy risk when used with amiodarone or verapamil
• May enhance warfarin effects, requiring close monitoring
• Grapefruit products may increase drug concentration levels

Precaution

Regular monitoring of liver function and lipid levels is essential. Discontinue if muscle symptoms develop or liver enzymes elevate significantly. Use lower doses in elderly patients or those with kidney impairment. Avoid grapefruit products during treatment with Crescents Simvastatin.

Important Information

Crescents Simvastatin 20mg should be part of comprehensive cholesterol management including diet and exercise. Regular lipid profile monitoring assesses efficacy and guides treatment adjustments. Store at room temperature, protected from light and moisture. Continue lifestyle modifications alongside medication therapy for optimal cardiovascular benefits.