Daflon 500mg Tablet is a specialized vascular medication containing micronized purified flavonoid fraction (MPFF). The formulation consists of 90% diosmin and 10% hesperidin, naturally occurring bioflavonoids with significant vascular protective properties. This vascular protective medication effectively treats venous insufficiency and hemorrhoidal conditions.
Uses
Daflon 500mg Tablet treats symptoms of chronic venous insufficiency including leg pain, heaviness, cramps, and edema. It also manages acute hemorrhoidal episodes and chronic hemorrhoidal disease. Additional uses include treating post-thrombotic syndrome, venous leg ulcers, and lymphedema.
Benefits
- Reduces venous inflammation
- Improves venous tone and elasticity
- Decreases venous distensibility
- Strengthens capillary resistance
- Reduces leg heaviness and pain
- Alleviates nighttime cramps
- Improves microcirculation
- Reduces hemorrhoidal pain and bleeding
- Accelerates healing of venous ulcers
- Well-tolerated with minimal side effects
How It Works
Daflon 500mg works through multiple mechanisms to improve venous function. It increases venous tone by prolonging the activity of norepinephrine on vessel walls. The medication reduces inflammation by inhibiting leukocyte adhesion and activation. It also improves lymphatic drainage and protects microcirculation by reducing capillary hyperpermeability.
Duration of Action
Therapeutic effects begin within 2 weeks of regular use for venous symptoms. Maximum clinical benefits are typically observed after 4-8 weeks of consistent treatment. Some patients may notice initial improvement in hemorrhoidal symptoms within 3-5 days.
Dosage
Condition |
Recommended Dosage |
Frequency |
Chronic venous insufficiency |
500mg (1 tablet) |
Twice daily |
Acute hemorrhoids |
1500mg (3 tablets) |
Days 1-4, then 1000mg (2 tablets) for 3 days |
Venous ulcers |
500mg (1 tablet) |
Twice daily |
Maintenance therapy |
500mg (1 tablet) |
Once or twice daily |
Warnings
Although Daflon 500mg is generally safe, it should not be used in patients with known hypersensitivity to any of its components. Daflon is not a substitute for other specific treatments such as compression therapy or surgery when indicated. Consult a healthcare provider if symptoms persist or worsen despite treatment.
Side Effects
Side effects are generally mild and infrequent, potentially including mild gastrointestinal disturbances such as nausea, diarrhea, or abdominal discomfort. Rare cases of dizziness, headache, malaise, or skin rash have been reported. Discontinue use and consult a healthcare provider if significant adverse reactions occur.
Pregnancy and Breastfeeding
Limited data exists on Daflon use during pregnancy, though available evidence suggests no harmful effects. As a precaution, use during pregnancy should be under medical supervision. Small amounts may pass into breast milk, though no adverse effects have been reported in breastfed infants.
Interactions
- Anticoagulants (potential minor interactions, monitor regularly)
- NSAIDs (generally safe but monitor with long-term combined use)
- Antihypertensive medications (no significant interactions reported)
- Lipid-lowering drugs (no known significant interactions)
- Oral contraceptives (no clinically relevant interactions identified)
- Antidiabetic medications (generally compatible)
Precautions
Take Daflon 500mg tablets at mealtimes to improve absorption and reduce potential gastrointestinal discomfort. Maintain regular usage for optimal effectiveness, especially for chronic conditions. Daflon works best when combined with lifestyle modifications such as regular exercise, weight management, and avoiding prolonged standing. Elevate legs when possible if suffering from venous insufficiency.
Important Information
Daflon 500mg is most effective when used as part of a comprehensive approach to venous health. For venous insufficiency, combining Daflon with compression therapy often yields better results than either treatment alone. Regular follow-up with healthcare providers is recommended to assess treatment progress and make necessary adjustments.
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