Dermazin Cream 25g (Silver Sulphadiazine)

Dermazin Cream, containing 1% Silver Sulphadiazine, is a topical antimicrobial agent primarily used for the treatment of burn wounds. This specialized formulation combines the antibacterial properties of silver with the broad-spectrum antimicrobial action of sulphadiazine, providing effective protection against infection in burn injuries.

Uses

Dermazin Cream 25g is primarily used for the prevention and treatment of infections in second and third-degree burns. It’s also effective in managing other types of wounds, including:

• Leg ulcers
• Pressure sores
• Donor sites in skin grafting
• Extensive abrasions
• Finger-tip injuries

Benefits

• Provides broad-spectrum antimicrobial protection
• Helps prevent infection in burn wounds
• Promotes healing of damaged tissue
• Reduces inflammation and pain associated with burns
• Easy to apply and remove
• Forms a protective barrier over the wound
• Minimizes scarring in some cases
• Effective against many strains of bacteria, including some antibiotic-resistant strains

How It Works

Silver Sulphadiazine works through a dual mechanism. The silver ions in the cream provide direct antimicrobial action, disrupting bacterial cell walls and interfering with DNA replication. The sulphadiazine component acts as a sulfonamide antibiotic, inhibiting bacterial growth by interfering with folic acid synthesis. This combination provides comprehensive protection against a wide range of microorganisms.

Dosage

Apply a 1/16 inch (1.5 mm) thick layer of Dermazin Cream to the affected area once or twice daily, or as directed by your healthcare provider. The cream should be gently spread to cover the entire wound area. For best results, the wound should be cleaned and debrided before each application.

Side Effects

While generally well-tolerated, some patients may experience side effects such as:

• Skin irritation or burning sensation
• Rash or itching
• Temporary discoloration of the skin In rare cases, more serious side effects like leukopenia (low white blood cell count) may occur. If you notice any unusual symptoms, contact your healthcare provider immediately.

Warning

Dermazin Cream is for external use only. Avoid contact with eyes and mucous membranes. If you have a known allergy to sulfonamides or silver compounds, do not use this product. Discontinue use and seek medical attention if you develop signs of an allergic reaction or if the wound shows signs of worsening infection.

Pregnancy and Breastfeeding

Pregnant women should use Dermazin Cream only if clearly needed and under close medical supervision. It’s not known if Silver Sulphadiazine passes into breast milk, so caution is advised for nursing mothers. Consult your healthcare provider before using this product if you are pregnant or breastfeeding.

Interaction

• May interact with enzymatic debriding agents, potentially reducing their effectiveness
• Could interfere with certain diagnostic tests, particularly those involving thyroid function
• Possible interaction with other topical medications applied to the same area
• May affect the absorption of other medications if used on large areas of the body

Important Information

Dermazin Cream should be used under the supervision of a healthcare professional, especially for extensive burns or wounds. Regular wound assessment is crucial during treatment. The cream may stain clothing or bedding, so take appropriate precautions. In case of ingestion, seek immediate medical attention. While effective, Dermazin Cream is not a substitute for proper wound care and overall burn management. Always follow your healthcare provider’s instructions for comprehensive burn treatment.