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Zoladex 10.8mg – Pre-filled Syringe of 10.8mg Injection

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Zoladex is a brand name for a medication called goserelin acetate. It is used for certain conditions, like prostate cancer, and gynecological disorders.


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Zoladex 10.8mg is an injectable luteinizing hormone-releasing hormone (LHRH) agonist used to treat prostate cancer, breast cancer, and endometriosis. It is administered as a subcutaneous depot injection that slowly releases over 12 weeks.


Under medical supervision, Zoladex 10.8mg injections can:

  • Treat prostate cancer when antiandrogen therapy is not appropriate
  • Suppress estrogen receptor-positive advanced breast cancer growth pre-surgery
  • Manage endometriosis symptoms like pelvic pain and discomfort
  • Provide an add-on treatment option alongside other therapies
  • Central precocious puberty
  • Transgender hormone therapy

Mechanism of Action

Zoladex lowers circulating sex hormones upon initial rise, providing sustained testosterone/estrogen suppression and slowing hormone-sensitive condition progression.1


Zoladex 10.8mg injections offer the advantage of convenient 12-week dosing, while:

  • Delivering consistent hormone level control
  • Minimizing testosterone flare symptoms
  • Allowing easy subcutaneous self-administration
  • Avoiding repeat office visits for monthly injections


10.8mg administered subcutaneously every 12 weeks. Follow all instructions from the managing healthcare provider, including guidance on concurrent medications.

How to Use

10.8mg administered as a subcutaneous injection once every 12 weeks. Follow all instructions from the managing healthcare provider, including guidance on injection sites and techniques.

Side Effects

Hot flashes, erectile dysfunction, decreased libido, pain at the injection site, headaches, depression, irritation, swelling, or itching at the administration site.


Goserelin acetate equivalent to 10.8mg Goserelin.

Warning Signs

Seek prompt attention if symptoms like shortness of breath, closure of the throat, facial swelling or hives occur, indicating hypersensitivity reactions.

Important Patient Information

Store unopened Zoladex refrigerated at 2-8°C until expired, away from children. Report any concerning side effects to your physician right away.

To use Zoladex, you will need to have it injected under the skin by your doctor or nurse. The injection is usually given in the lower abdomen or buttock.

Here are the steps on how to use Zoladex:

  1. Your doctor or nurse will clean the injection site with an alcohol swab.
  2. They will then insert the needle under the skin at a 45-degree angle.
  3. They will slowly inject the Zoladex medication.
  4. Once the injection is complete, they will remove the needle and apply a bandage to the injection site.

Zoladex is a slow-release medication, so you will only need to have it injected once every 3 or 12 weeks, depending on the condition being treated.

Here are some tips for using Zoladex:

  • Be sure to keep your appointment for your next Zoladex injection. It is important to have your injections on schedule to ensure that the medication is working effectively.
  • If you miss an injection, contact your doctor or nurse as soon as possible to reschedule.
  • Tell your doctor or nurse if you have any allergies to medications or any other medical conditions.
  • Tell your doctor or nurse about all of the medications you are taking, including over-the-counter medications, herbal supplements, and vitamins.
  • If you have any questions or concerns about using Zoladex, be sure to talk to your doctor or nurse.


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