Zoladex 10.8mg is an injectable luteinizing hormone-releasing hormone (LHRH) agonist used to treat prostate cancer, breast cancer, and endometriosis. It is administered as a subcutaneous depot injection that slowly releases over 12 weeks.
Uses
Under medical supervision, Zoladex 10.8mg injections can:
- Treat prostate cancer when antiandrogen therapy is not appropriate
- Suppress estrogen receptor-positive advanced breast cancer growth pre-surgery
- Manage endometriosis symptoms like pelvic pain and discomfort
- Provide an add-on treatment option alongside other therapies
- Central precocious puberty
- Transgender hormone therapy
Mechanism of Action
Zoladex lowers circulating sex hormones upon initial rise, providing sustained testosterone/estrogen suppression and slowing hormone-sensitive condition progression.1
Benefits
Zoladex 10.8mg injections offer the advantage of convenient 12-week dosing, while:
- Delivering consistent hormone level control
- Minimizing testosterone flare symptoms
- Allowing easy subcutaneous self-administration
- Avoiding repeat office visits for monthly injections
Dosage
10.8mg administered subcutaneously every 12 weeks. Follow all instructions from the managing healthcare provider, including guidance on concurrent medications.
How to Use
10.8mg administered as a subcutaneous injection once every 12 weeks. Follow all instructions from the managing healthcare provider, including guidance on injection sites and techniques.
Side Effects
Hot flashes, erectile dysfunction, decreased libido, pain at the injection site, headaches, depression, irritation, swelling, or itching at the administration site.
Composition
Goserelin acetate equivalent to 10.8mg Goserelin.
Warning Signs
Seek prompt attention if symptoms like shortness of breath, closure of the throat, facial swelling or hives occur, indicating hypersensitivity reactions.
Important Patient Information
Store unopened Zoladex refrigerated at 2-8°C until expired, away from children. Report any concerning side effects to your physician right away.
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