Fleming 1000mg Tablet is an advanced broad-spectrum antibiotic containing amoxicillin and clavulanic acid. This synergistic combination effectively treats a wide range of bacterial infections by overcoming resistance mechanisms that typically render amoxicillin alone ineffective.
Uses
Fleming 1000mg tablet is specifically prescribed for bacterial infections that have become resistant to other antibiotic treatments. Fleming 1000mg can treat illnesses including:
- Sinusitis
- Otitis media
- Typhoid Fever
- Cystitis
- Pneumonia
- Gonorrhea
- Respiratory tract infections
- Bone and joint infections
- Skin infections like abscesses
- Bacterial diarrhea
- Dental infections
The ingredients in Fleming tablets work synergistically to inhibit cell wall synthesis in penicillin-resistant bacteria, stopping the spread of infection.
Benefits
- Effective against penicillin-resistant bacteria
- Broad-spectrum antibiotic action
- Treats infections in multiple body systems
- Powerful synergistic combination
- Overcomes bacterial beta-lactamase enzymes
- Reduces risk of treatment failure
- Fewer treatment days compared to some alternatives
- Established safety and efficacy profile
How It Works
Fleming 1000mg Tablet works through a dual-mechanism approach. Amoxicillin inhibits bacterial cell wall synthesis, while clavulanic acid inactivates beta-lactamase enzymes that bacteria produce to resist penicillin antibiotics. This synergistic action effectively eliminates bacteria that would otherwise be resistant to amoxicillin alone.
Duration of Action
The medication maintains effective antibiotic levels in the body for approximately 12 hours after administration. Peak plasma concentrations are typically achieved within 1-2 hours after oral administration, supporting the twice-daily dosing schedule.
Dosage
Patient Type | Recommended Dosage | Frequency |
---|---|---|
Standard Adult Dose | 1 tablet (1000mg) | Every 12 hours |
Severe Infections | 2 tablets (2000mg) | Every 12 hours |
Renal Impairment | Dose adjustment required | Consult healthcare provider |
Warnings
Do not use Fleming 1000mg Tablet if you have a history of allergic reactions to penicillin antibiotics or clavulanic acid. Discontinue use and seek immediate medical attention if signs of an allergic reaction occur, such as rash, itching, swelling, severe dizziness, or difficulty breathing. This medication may cause liver damage in rare cases.
Side Effects
Common side effects include diarrhea, nausea, vomiting, and stomach discomfort. Less common effects may include headache, oral or vaginal candidiasis, and skin rash. Rare but serious side effects include severe allergic reactions, Clostridium difficile-associated diarrhea, and hepatic dysfunction.
Pregnancy and Breastfeeding
Fleming 1000mg Tablet is generally considered safe during pregnancy when clearly needed. The medication passes into breast milk in small amounts. Pregnant or breastfeeding women should consult their healthcare provider before using this medication.
Interactions
- Probenecid (increases amoxicillin levels)
- Allopurinol (increased risk of skin rash)
- Oral contraceptives (potential reduced effectiveness)
- Anticoagulants (potential altered effects)
- Methotrexate (increased risk of toxicity)
- Mycophenolate mofetil (decreased effectiveness)
- Oral typhoid vaccine (reduced immune response)
Precautions
Take Fleming 1000mg Tablet at evenly spaced intervals to maintain consistent antibiotic levels. Complete the full prescribed course even if symptoms improve before completion. Take with meals to minimize stomach upset. Store at room temperature away from moisture and heat. Monitor for signs of superinfection such as persistent diarrhea or new infections.
Important Information
Fleming 1000mg Tablet should be taken exactly as prescribed. Always complete the full course of treatment even if symptoms improve. Skipping doses or not completing the full course may result in decreased effectiveness and increased bacterial resistance. If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose.
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Customer questions & answers
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can i take fleming 1000 with rifampin
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A
Hello Cynthia,
Fleming 1000mg and Rifampin can be taken together in certain cases, especially when prescribed by a doctor for specific infections like tuberculosis or resistant bacterial infections.
However, combining these two antibiotics should only be done under medical supervision, as Rifampin can reduce the effectiveness of other medications, including some antibiotics.
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