Humulin 70/30 is a prescription insulin product containing a mixture of 70% NPH human insulin isophane suspension and 30% regular human insulin. This dual-acting insulin formulation provides both intermediate-acting and short-acting insulin coverage for effective blood glucose management in diabetes patients.
Uses
Humulin 70/30 is prescribed for blood sugar control in adults with type 1 or type 2 diabetes mellitus. It helps manage both fasting and post-meal blood glucose levels through its unique combination of insulin types, providing comprehensive daily glycemic control.
Benefits
- Provides both basal and prandial glucose control
- Offers convenient twice-daily dosing
- Reduces need for multiple insulin injections
- Helps maintain consistent blood sugar levels
- Improves overall glycemic control
- Decreases risk of diabetes complications
- Cost-effective diabetes management option
- Suitable for many diabetes treatment plans
How It Works
The regular insulin component acts quickly to control blood sugar after meals, while the NPH component provides longer-lasting coverage. The 70/30 ratio ensures balanced glucose control throughout the day, with peak action occurring between 2-4 hours after injection.
Dosage
| Patient Type | Starting Dose | Timing |
|---|---|---|
| New to Insulin | Individualized based on weight and blood sugar | Twice daily, 30 mins before meals |
| Switching from other insulin | Calculate equivalent dose | Morning and evening, 30 mins before meals |
Duration of Action
Onset begins within 30 minutes of injection. Peak effect occurs between 2-4 hours, with a duration of action lasting 14-24 hours. The dual-action formula provides coverage for both immediate and extended blood sugar control.
Side Effects
Common side effects include injection site reactions, hypoglycemia, and weight gain. More serious side effects may include severe hypoglycemia, allergic reactions, or changes in potassium levels. Monitor blood sugar regularly and report concerning symptoms to your healthcare provider.
Warning
Risk of severe hypoglycemia if dosage is miscalculated or meals are missed. Never share insulin pens or syringes. Store properly and check expiration dates. Seek immediate medical attention for severe hypoglycemia or allergic reactions.
Pregnancy and Breastfeeding
Humulin 70/30 can be used during pregnancy and breastfeeding under medical supervision. Insulin requirements often change during pregnancy, requiring careful monitoring and dose adjustments.
Interactions
- Beta-blockers may mask hypoglycemia symptoms
- Corticosteroids can increase insulin requirements
- Certain diabetes medications may enhance effects
- Some antidepressants may affect blood sugar
- Alcohol may intensify hypoglycemic effects
Precautions
Regular blood glucose monitoring is essential. Rotate injection sites to prevent lipodystrophy. Keep glucose tablets or sugar source readily available. Adjust doses for exercise, illness, or significant diet changes. Store unopened vials in refrigerator and in-use vials at room temperature.
Important Information
Inspect Humulin 70/30 before each use – it should appear uniformly cloudy after mixing. Never freeze or expose to extreme heat. Carry medical identification indicating diabetes and insulin use. Regular medical check-ups are essential for dose adjustments and complication prevention. With proper use of Humulin 70/30, maintain consistent meal timing and daily activity patterns for optimal blood sugar control.
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