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INS Letrozole 2.5mg Tablet x30

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INS Letrozole 2.5mg Tablet is used for breast cancer treatment and as a fertility enhancement therapy for women experiencing ovulatory disorders.

16,000.00

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INS Letrozole 2.5mg Tablet contains Letrozole, a non-steroidal aromatase inhibitor that reduces estrogen production in the body. While originally developed for breast cancer treatment, it has become an effective first-line medication for treating infertility in women with ovulatory disorders.

Uses

INS Letrozole 2.5mg Tablet is used for treating hormone-dependent breast cancer in postmenopausal women. It is also increasingly prescribed as a fertility treatment for women with polycystic ovary syndrome (PCOS), unexplained infertility, and anovulation. The medication stimulates ovulation and increases the chances of successful conception.

Benefits

  • Effectively induces ovulation in anovulatory women
  • Higher live birth rates compared to some traditional fertility medications
  • Lower risk of multiple pregnancies than other fertility treatments
  • Fewer side effects than clomiphene citrate
  • Short half-life reduces exposure to developing follicles
  • May improve pregnancy outcomes in PCOS patients
  • Cost-effective fertility treatment option
  • Can be effective in clomiphene-resistant patients

How It Works

INS Letrozole 2.5mg Tablet works by temporarily inhibiting the enzyme aromatase, which is responsible for converting androgens to estrogens. This temporary reduction in estrogen levels triggers the pituitary gland to increase follicle-stimulating hormone (FSH) production, stimulating ovarian follicle development and ovulation in women with fertility issues.

Duration of Action

The medication has a half-life of approximately 48 hours. When used for fertility treatment, it is typically administered for 5 days early in the menstrual cycle, with ovulation usually occurring 5-10 days after the last dose.

Dosage

Condition Recommended Dosage Duration
Infertility treatment 2.5-5mg Days 3-7 of cycle
Advanced breast cancer 2.5mg Continuous daily
Adjuvant breast cancer 2.5mg 5 years daily

Warnings

Do not use INS Letrozole 2.5mg Tablet if you are pregnant as it may harm the developing fetus. The medication is contraindicated in premenopausal women except when specifically used for fertility treatment. Patients with severe liver impairment should use with caution under close medical supervision.

Side Effects

Common side effects include hot flashes, night sweats, fatigue, headache, joint pain, muscle pain, bone pain, and mild nausea. Less common effects include mood changes, dizziness, insomnia, peripheral edema, and skin rash. Most side effects are mild to moderate when used short-term for fertility treatment.

Pregnancy and Breastfeeding

INS Letrozole 2.5mg Tablet is absolutely contraindicated during pregnancy. When used for fertility treatment, it should be discontinued immediately if pregnancy occurs. Women should wait at least 3 days after the last dose before attempting conception to ensure the medication has cleared from the body.

Interactions

  • Tamoxifen (reduced letrozole efficacy)
  • Strong CYP2A6 inhibitors (increased letrozole levels)
  • Strong CYP3A4 inducers (decreased letrozole efficacy)
  • Estrogen-containing medications (reduced therapeutic effect)
  • Hormone replacement therapy (antagonistic effects)
  • Warfarin (potential increased anticoagulant effect)

Precautions

Take INS Letrozole 2.5mg Tablet exactly as prescribed by your fertility specialist. Follicular development and ovulation should be monitored using ultrasound and hormone tests during treatment cycles. Regular bone density monitoring may be recommended for long-term use. Discuss all medications and supplements with your doctor before starting treatment.

Important Information

INS Letrozole 2.5mg Tablet is often used “off-label” for fertility treatment, meaning this use is not included in the manufacturer’s original FDA approval. Despite this, extensive research supports its efficacy and safety for fertility treatment when properly prescribed and monitored by a reproductive specialist.

Product Image Highlights

Letrozole Tablet
Letrozole
Letrozole
Letrozole 2.5mg

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Category Dosage Instructions
Infertility (Ovulation induction) 2.5 mg once daily for 5 days, usually starting on Day 3, 4, or 5 of the menstrual cycle
Breast Cancer (Postmenopausal women) 2.5 mg once daily, long-term treatment for up to 5 years or as directed
Advanced/Metastatic Breast Cancer 2.5 mg once daily until disease progression is evident

How to Use:

  • Take the tablet at the same time each day, with or without food.

  • Follow your doctor’s instructions for timing during menstrual cycle if using for infertility.

  • Do not exceed the prescribed dosage.


Important Information:

  • Not recommended in premenopausal women unless prescribed for fertility treatment.

  • Inform your doctor if you have liver or kidney issues.

  • May cause dizziness or fatigue—avoid driving if affected.

  • Not for use during pregnancy unless prescribed for fertility purposes.

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