Isordil 10mg Tablet (Isosorbide Dinitrate) x50

Isordil 10mg Tablet contains Isosorbide Dinitrate, a nitrate vasodilator that relaxes blood vessels. This sublingual formulation is designed for rapid absorption and quick relief of angina symptoms while helping to prevent future angina attacks.

Uses

Isordil Tablet  Sublingual treats and prevents angina pectoris (chest pain due to coronary artery disease). It can be used for acute relief during an angina attack or as preventive therapy before activities that might trigger angina. It’s also sometimes prescribed as part of heart failure management.

Benefits

• Provides quick relief of acute angina attacks
• Prevents angina episodes when taken before physical exertion
• Reduces workload on the heart
• Improves blood flow to heart muscle
• Enhances exercise tolerance
• Decreases frequency and severity of angina episodes
• Works rapidly via sublingual administration
• May reduce hospitalization in chronic stable angina
• Complements other anti-anginal medications

How It Works

Isordil works by releasing nitric oxide in the body, which relaxes vascular smooth muscle and dilates blood vessels. This vasodilation reduces cardiac workload by decreasing preload and afterload, improving oxygen supply to the heart while reducing oxygen demand, thereby relieving angina symptoms.

Dosage

For sublingual use, place tablet under tongue and allow to dissolve completely. Do not swallow, chew, or drink until dissolved.

Duration of Action

Isordil begins working within 2-5 minutes when used sublingually. Effects peak around 15-30 minutes and last approximately 1-2 hours. For preventive use, take 15 minutes before anticipated exertion. Develop a schedule with your doctor to maintain effectiveness throughout the day.

Side Effects

Common side effects include headache, dizziness, lightheadedness, and flushing. These often diminish as your body adjusts to the medication. Temporary drops in blood pressure may cause fainting, especially when standing quickly. Contact your doctor if side effects are severe or persistent.

Warning

Avoid alcohol while taking Isordil as it can cause dangerous blood pressure drops. Never take with erectile dysfunction medications like sildenafil, as this combination can cause life-threatening hypotension. Sit or lie down at first sign of dizziness. Seek emergency care for severe headache, blurred vision, or fainting.

Pregnancy and Breastfeeding

Isordil should be used during pregnancy only when clearly needed and potential benefits outweigh risks. Limited data exists on safety during pregnancy. It is not known whether isosorbide dinitrate passes into breast milk. Consult your healthcare provider before using while breastfeeding.

Interaction

• Severe hypotension when combined with PDE-5 inhibitors (erectile dysfunction drugs)
• Increased hypotensive effects with alcohol
• Enhanced blood pressure reduction with other antihypertensives
• Possible reduced effectiveness with concurrent calcium channel blockers
• May interact with certain medications for migraines

Precaution

Use with caution in patients with low blood pressure, volume depletion, or heart conditions like hypertrophic cardiomyopathy. May cause severe hypotension when rising from sitting/lying position. Elderly patients may be more sensitive to blood pressure effects. Tolerance may develop with continuous use; follow doctor’s instructions about dosing schedule.

Important Information

Keep Isordil in original light-resistant container at room temperature. Replace tablets every 6 months as potency may decrease. Medication tolerance can develop; follow your doctor’s dosing schedule to minimize this effect. Carry identification indicating you use nitrates. Maintain regular medical follow-ups to assess effectiveness and adjust dosage if needed.