Keppra 250mg is an advanced antiepileptic medication containing levetiracetam. This prescription medication effectively manages various types of seizures by regulating brain electrical activity. It’s valued for its broad spectrum of activity and favorable safety profile in epilepsy management.
Uses
Keppra 250mg treats multiple types of seizures, including partial-onset seizures, myoclonic seizures in juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures in idiopathic generalized epilepsy. It can be used alone or combined with other antiepileptic medications.
Benefits
- Controls multiple types of seizures
- High efficacy in seizure reduction
- Suitable for monotherapy or combination therapy
- Shows consistent therapeutic response
- Well-tolerated by most patients
- Minimal drug interactions
- Convenient twice-daily dosing
- Appropriate for long-term use
How It Works
Keppra works by binding to SV2A protein in brain cells, modulating neurotransmitter release and reducing abnormal electrical activity in the brain. This unique mechanism helps prevent seizure occurrence and promotes better seizure control.
Dosage
Patient Type | Dosage | Duration and Frequency |
---|---|---|
Initial Adult | 250mg | Twice daily, increase as needed |
Maintenance Adult | 500-1500mg | Twice daily, adjust to response |
Elderly/Renal Impaired | 250mg | Twice daily, adjust based on clearance |
Duration of Action
Therapeutic effects begin within 1-2 weeks of consistent use. Peak plasma levels achieved within 1 hour of administration. Steady-state concentrations reached after 2 days of twice-daily dosing.
Side Effects
Common side effects include somnolence, fatigue, dizziness, and behavioral changes. Serious side effects may include mood changes, suicidal thoughts, or severe skin reactions. Most side effects are manageable and decrease over time.
Warning
Seek immediate medical attention if experiencing suicidal thoughts, severe skin reactions, or mood changes. Do not stop medication abruptly as this may trigger seizures. Any dosage changes should be supervised by healthcare provider.
Pregnancy and Breastfeeding
Benefits may outweigh risks during pregnancy; requires careful evaluation. Compatible with breastfeeding but monitoring of infant for drowsiness is recommended.
Interactions
- Other antiepileptic drugs
- CNS depressants
- Methotrexate
- Oral contraceptives
- Probenecid
Precautions
Regular monitoring of kidney function required. Avoid alcohol consumption. Exercise caution when driving or operating machinery until response is known. Report any unusual mood changes or behavioral symptoms promptly.
Important Information
Take Keppra 250mg exactly as prescribed. Never skip doses or stop suddenly without medical advice. Keep regular follow-up appointments for monitoring treatment effectiveness and side effects. Maintain a seizure diary to track frequency and patterns. Store at room temperature away from moisture. Keep emergency contact information readily available.
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