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Pitrofin Syrup (Phenobarbitone) x60ml

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Pitrofin Syrup is used to treat and prevent various types of seizures, including epilepsy, also used for anxiety, insomnia, or as a pre-operative sedative.

5,000.00

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Availability: In Stock
SKU:PIT744

Pitrofin Syrup contains phenobarbitone, a long-acting barbiturate medication renowned for its anticonvulsant properties and sedative effects, primarily utilized in the management of seizure disorders and short-term treatment of anxiety and insomnia.

Uses

Pitrofin Syrup is principally prescribed for the treatment and prevention of various seizure types, including generalized and partial seizures associated with epilepsy. It’s also employed in the short-term management of severe anxiety, insomnia resistant to other treatments, and as a pre-operative sedative to reduce anxiety before surgical procedures.

Benefits

  • Highly effective in controlling and preventing various types of seizures
  • Provides potent sedative effects for severe anxiety and treatment-resistant insomnia
  • Long-acting formulation allows for less frequent dosing, improving adherence
  • Versatile use as a pre-operative medication to reduce patient anxiety
  • Can be valuable in managing alcohol withdrawal symptoms
  • May offer neuroprotective effects in certain conditions

How It Works

Phenobarbitone exerts its therapeutic effects by enhancing the activity of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the central nervous system. This enhancement amplifies the inhibitory effects of GABA, resulting in decreased neuronal excitability and reduced abnormal electrical activity in the brain, thus controlling seizures and producing anxiolytic and sedative effects.

Duration of Action

With its exceptionally long half-life of approximately 79 hours in adults, phenobarbitone provides prolonged therapeutic effects, often lasting several days after the last dose. Steady-state concentrations are typically achieved within 2-3 weeks of regular dosing, ensuring consistent seizure control and therapeutic efficacy.

Dosage

The dosage of Pitrofin Syrup is highly individualized and depends on the specific condition being treated, patient age, weight, and individual response to therapy. Typical adult dosages for seizure control range from 30-120 mg per day, often divided into two or three doses. Your healthcare provider will determine the most appropriate dosage regimen based on your specific needs and monitor you closely for optimal therapeutic response.

Side Effects

While generally well-tolerated, Pitrofin Syrup may cause side effects such as drowsiness, dizziness, nausea, and impaired coordination. More serious adverse effects, although rare, can include severe allergic reactions, mood alterations, cognitive impairment, and hepatotoxicity. Immediate medical attention is crucial if you experience any severe or persistent side effects.

Warning

Phenobarbitone carries a risk of physical dependence and can be habit-forming, particularly with long-term use or high doses. Abrupt discontinuation may precipitate withdrawal symptoms or increased seizure activity. Always consult your healthcare provider before making any changes to your dosage regimen.

Pregnancy and Breastfeeding

Pitrofin Syrup poses significant risks during pregnancy and may cause congenital malformations. It should only be used in pregnant women when the potential benefits clearly outweigh the risks. The medication can also pass into breast milk and may cause adverse effects in nursing infants. Thorough discussion with your healthcare provider is essential if you are pregnant, planning to become pregnant, or breastfeeding.

Interactions

  • May potentiate the effects of other central nervous system depressants, including alcohol
  • Can significantly decrease the efficacy of hormonal contraceptives
  • May alter the metabolism and effectiveness of various medications through enzyme induction
  • Can interact with certain antidepressants, potentially leading to increased side effects
  • May reduce the effectiveness of vitamin D and calcium supplements

Important Information

Strict adherence to the prescribed dosage regimen of Pitrofin Syrup is crucial for optimal therapeutic outcomes. Regular monitoring, including blood tests to assess liver function and drug levels, is essential throughout treatment. Exercise caution when engaging in activities requiring mental alertness, as this medication may impair cognitive and motor functions. Maintain open communication with your healthcare provider, reporting any changes in your condition or concerns about side effects promptly.

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Customer questions & answers

    Another use of pitrofin in kids apart from anxiety...
  1. 0 votes
    Q Another use of pitrofin in kids apart from anxiety... answer now
    Asked by Ifeoma on November 15, 2024 12:04 am
    A

    Hello Ifeoma,

     

    Pitrofin Syrup (Phenobarbitone) is primarily used to manage anxiety and seizures in children. It may also be prescribed as a sedative or to help calm children with certain behavioral conditions, but always follow a doctor's guidance for its use.

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Age Group Dosage
Adults 5-10 mL (1-2 teaspoons) once or twice daily
Children (1-5 years) 2.5-5 mL (1/2-1 teaspoon) once or twice daily
Children (6-12 years) 5-10 mL (1-2 teaspoons) once or twice daily
Infants (under 1 year) 1-2 mL (1/4-1/2 teaspoon) once or twice daily

How to Use

  • Shake well before use.
  • Administer the syrup orally, preferably before meals.
  • Follow the prescribed dosage by your healthcare provider.

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