Klovinal Vaginal Pessary Insert x6

Klovinal Vaginal Pessary is a unique combination medication containing clotrimazole (antifungal), metronidazole (antibiotic), and Lactobacillus spores (probiotic). This comprehensive formulation treats various vaginal infections while promoting overall vaginal health.

Uses

Klovinal Vaginal Pessary treats vulvovaginal candidiasis (yeast infections), bacterial vaginosis, trichomoniasis, and mixed vaginal infections. It effectively combats conditions causing itching, burning, and abnormal discharge while restoring vaginal microbiome balance.

Benefits

• Offers combination therapy for comprehensive treatment
• Provides targeted delivery of active ingredients directly to infection site
• Supports vaginal microbiome restoration with beneficial probiotics
• Convenient and discreet self-administered treatment option
• Addresses multiple types of vaginal infections simultaneously
• Reduces need for multiple separate medications
• Promotes long-term vaginal health maintenance
• Minimizes systemic side effects through localized treatment

How It Works

Clotrimazole inhibits fungal cell wall synthesis to eliminate yeast infections. Metronidazole targets anaerobic bacteria causing bacterial vaginosis and trichomoniasis. Lactobacillus spores help restore beneficial vaginal flora, creating an acidic environment that prevents reinfection and maintains healthy vaginal pH.

Dosage

Insert one Klovinal pessary deep into the vagina before bedtime. Use the provided applicator for proper placement.

Duration of Action

Klovinal begins working immediately upon insertion, with symptom relief typically occurring within 24-48 hours. The medication provides sustained release over 8-12 hours per dose. Complete infection clearance usually occurs within the 6-day treatment course, with microbiome restoration continuing for several weeks.

Side Effects

Common side effects include mild vaginal irritation, temporary discharge, and abdominal cramping. Some women may experience vaginal burning or itching initially. Rare but serious side effects include severe allergic reactions, persistent gastrointestinal disturbances, or neurological symptoms requiring immediate medical attention.

Warning

Avoid alcohol consumption during treatment and for 24 hours after completion due to metronidazole interaction. Do not use if allergic to any components. Klovinal may damage latex condoms and diaphragms. Consult healthcare provider if symptoms worsen or persist beyond treatment completion.

Pregnancy and Breastfeeding

Consult healthcare provider before using Klovinal during pregnancy, especially in the first trimester. The combination’s safety during breastfeeding is not fully established. Alternative treatments may be recommended for pregnant or nursing women depending on infection severity and gestational stage.

Interaction

• May reduce effectiveness of latex contraceptives and barrier methods
• Metronidazole component interacts with alcohol causing severe nausea
• Possible reduced efficacy when used with other vaginal medications simultaneously
• May interact with oral anticoagulants if systemically absorbed
• Could affect absorption of other vaginal treatments used concurrently

Precaution

Complete the full treatment course even if symptoms improve early. Avoid tampons, douches, or vaginal intercourse during treatment. Wash hands thoroughly before and after application. Store pessaries in a cool, dry place. Partners may require simultaneous treatment to prevent reinfection.

Important Information

Klovinal is available by prescription only and requires proper medical diagnosis before use. Inform healthcare provider of complete medical history including allergies and current medications. If symptoms persist after treatment completion, follow-up examination may be necessary to rule out other conditions. Maintain good vaginal hygiene practices to prevent future infections.