Oxispa 500mg Tablets (Cefuroxime) x10

Oxispa 500mg is an oral cephalosporin antibiotic medication containing cefuroxime axetil as its active ingredient. It provides effective treatment against a wide range of bacterial infections by inhibiting bacterial cell wall synthesis.

Uses

Oxispa 500mg tablet treats mild to moderate bacterial infections including early Lyme disease, typhoid fever, pharyngitis/tonsillitis, secondary infections of acute bronchitis, uncomplicated gonorrhea, and uncomplicated skin and skin structure infections. It is effective against many gram-positive and gram-negative bacteria.

Benefits

• Broad-spectrum antimicrobial activity
• Effective against many resistant bacteria
• Convenient twice-daily dosing
• Good tissue penetration
• Well-established safety profile
• High oral bioavailability
• Treats multiple infection types
• Extended half-life allows less frequent dosing

How It Works

Oxispa 500mg works by interfering with bacterial cell wall synthesis. Cefuroxime binds to specific penicillin-binding proteins located inside the bacterial cell wall, inhibiting the final step of peptidoglycan synthesis. This destabilizes the bacterial cell wall, causing cell rupture and death while preventing bacterial reproduction.

Duration of Action

The antimicrobial effects of Oxispa 500mg typically last 12 hours, with peak plasma concentrations occurring 2-3 hours after administration. The half-life is approximately 1.5 hours, allowing for twice-daily dosing schedules.

Dosage

Warnings

Do not use Oxispa 500mg if you have a known allergy to cephalosporin antibiotics or penicillins. Complete the full course of treatment even if symptoms improve. Prolonged use may result in superinfection. Monitor for signs of Clostridium difficile-associated diarrhea.

Side Effects

Common side effects include diarrhea, nausea, vomiting, abdominal pain, headache, and skin rash. Less common effects include dizziness, drowsiness, and temporary changes in taste. Rare but serious side effects include severe allergic reactions, liver problems, and blood disorders.

Pregnancy and Breastfeeding

Oxispa 500mg should be used during pregnancy only when clearly needed. Benefits must outweigh potential risks. Small amounts of cefuroxime pass into breast milk. Consult your healthcare provider before using while breastfeeding.

Interactions

• Probenecid (increases cefuroxime levels)
• Antacids and H2-blockers (reduced absorption)
• Oral contraceptives (possible reduced effectiveness)
• Loop diuretics (increased risk of kidney toxicity)
• Anticoagulants (possible enhanced effect)
• Nephrotoxic drugs (increased risk of kidney problems)

Precautions

Take Oxispa 500mg with food to enhance absorption and reduce stomach upset. Store at room temperature away from moisture and heat. If you miss a dose, take it as soon as you remember unless it’s nearly time for your next dose. Keep well hydrated during treatment. Diabetic patients should monitor blood glucose levels as false positive results may occur in some urine glucose tests.

Important Information

Oxispa 500mg is a prescription-only medication that must be used under medical supervision. Taking antibiotics when not needed may reduce their effectiveness in future infections. Do not share this medication with others. Take exactly as prescribed at evenly spaced intervals to maintain consistent blood levels for optimal effectiveness.