Pilorem 80/10 Tablet (Telmi+Amlodipine) x30

Pilorem 80/10 Tablet is a combination medication containing Telmisartan 80mg and Amlodipine 10mg. This fixed-dose combination effectively treats hypertension through dual mechanisms, offering superior blood pressure control for patients requiring multiple antihypertensive agents.

Uses

Pilorem 80/10 is prescribed for the management of high blood pressure in patients who require dual therapy. It’s particularly suitable for patients whose blood pressure is not adequately controlled on either telmisartan or amlodipine alone.

Benefits

• Provides dual mechanism blood pressure control
• Reduces pill burden with fixed-dose combination
• Offers 24-hour blood pressure control
• Superior efficacy compared to monotherapy
• Better compliance due to once-daily dosing
• Reduces cardiovascular risk
• Well-tolerated combination therapy
• Complementary mechanisms of action
• Cost-effective treatment option
• Improved patient adherence

How It Works

Telmisartan blocks angiotensin II receptors, reducing blood vessel constriction and decreasing blood pressure. Amlodipine, a calcium channel blocker, relaxes blood vessels and reduces peripheral resistance, further lowering blood pressure through a complementary mechanism.

Duration of Action

Onset of action begins within 2 hours of administration. The combination provides effective 24-hour blood pressure control with once-daily dosing. Full therapeutic effect is typically achieved within 2-4 weeks of regular use.

Dosage

Take one tablet once daily, preferably at the same time each day. Can be taken with or without food. Do not exceed the prescribed dose. Regular blood pressure monitoring is recommended.

Side Effects

Common effects of Pilorem 80/10 Tablet include dizziness, ankle swelling, headache, and fatigue. Less common effects include palpitations, flushing, and mild gastrointestinal disturbances. Most side effects are mild and diminish over time.

Warning

Immediate medical attention needed if experiencing chest pain, severe dizziness, or fainting. Avoid abrupt discontinuation. Regular monitoring of blood pressure and kidney function recommended.

Pregnancy and Breastfeeding

 Pilorem 80/10 Tablet is contraindicated during pregnancy due to risk of fetal harm. Not recommended during breastfeeding. Consult healthcare provider for alternative treatment options.

Interactions

• May interact with NSAIDs
• Potential interaction with potassium supplements
• Can interact with other blood pressure medications
• May affect lithium levels
• Interacts with grapefruit juice
• Could enhance effects of beta-blockers
• Possible interaction with diuretics
• May interact with certain antidepressants
• Can affect digoxin levels
• Potential interaction with statins

Important Information

Regular blood pressure monitoring required. Take Pilorem 80/10 Tablet consistently at same time daily. Report any unusual side effects to healthcare provider. Maintain healthy lifestyle changes alongside medication. Avoid salt substitutes containing potassium. Keep track of blood pressure readings.