Seretide Diskus 50/250mcg Inhaler

Seretide Diskus 50/250 mcg combines salmeterol (a long-acting beta-2 agonist) and fluticasone propionate (an inhaled corticosteroid). This advanced inhaler delivers precise doses of medication for comprehensive management of asthma and COPD, providing both immediate bronchodilation and long-term inflammation control.

Uses

Seretide Diskus is prescribed for ongoing management of moderate to severe asthma and COPD in adults. It’s specifically indicated for patients whose symptoms aren’t adequately controlled with single-ingredient inhalers. The medication prevents and controls chronic respiratory symptoms while reducing exacerbations.

Benefits

• Provides dual-action respiratory treatment
• Delivers up to 12 hours of bronchodilation
• Reduces airway inflammation effectively
• Decreases frequency of asthma attacks
• Improves overall lung function
• Reduces need for rescue inhalers
• Enhances quality of life for respiratory patients
• Offers convenient twice-daily dosing

How It Works

The dual-action mechanism involves salmeterol relaxing airway smooth muscles for immediate breathing relief, while fluticasone propionate reduces inflammation in the airways. This combination provides both rapid symptom relief and long-term disease control through sustained anti-inflammatory action.

Duration of Action

Bronchodilation effects begin within 10-20 minutes, lasting up to 12 hours. Anti-inflammatory benefits develop over several days, with optimal results typically achieved after 1-2 weeks of regular use. Consistent use is essential for maintaining therapeutic effects.

Dosage

One inhalation twice daily, approximately 12 hours apart. Morning and evening dosing is recommended. Never exceed prescribed dose. Use the inhaler at the same times each day for optimal results. Proper inhalation technique is crucial for medication effectiveness.

Side Effects

Common effects of Seretide Diskus include throat irritation, hoarseness, and oral candidiasis. Less frequent effects may include tremors, palpitations, and mild anxiety. Serious but rare effects include severe allergic reactions and paradoxical bronchospasm.

Warning

Not for rescue use during acute bronchospasm. Monitor for signs of oral thrush. Children require regular growth monitoring. Patients with milk protein allergy should exercise caution. Seek immediate medical attention if breathing significantly worsens after use.

Pregnancy and Breastfeeding

Only use Seretide Diskus during pregnancy only if benefits outweigh risks. Discuss with healthcare provider if pregnant or planning pregnancy. Limited data available for use during breastfeeding – requires careful risk-benefit assessment.

Interactions

• Beta-blockers may reduce effectiveness
• Strong CYP3A4 inhibitors may increase systemic exposure
• Caution with other sympathomimetic agents
• May interact with certain antifungals
• Monitor with diuretic therapy

Important Information

Rinse mouth after each use to prevent thrush. Store at room temperature below 30°C. Check dose counter regularly. Keep inhaler dry. Don’t stop treatment abruptly. Clean mouthpiece weekly with dry tissue. Replace inhaler when counter shows zero or by expiry date, whichever comes first.