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Diamicron MR 60mg (Gliclazide) Tabs x30

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Diamicron MR 60mg is use for treatment of type 2 diabetes mellitus in patients who cannot achieve adequate glycemic control through diet, and exercise alone.


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Diamicron MR 60mg is an extended-release formulation of gliclazide, a second-generation sulfonylurea medication used in the management of type 2 diabetes mellitus. It is designed to provide sustained blood glucose control throughout the day with once-daily dosing.


 Diamicron MR 60mg is indicated for the treatment of type 2 diabetes mellitus in patients who cannot achieve adequate glycemic control through diet, exercise, and weight reduction alone. It can be used as monotherapy or in combination with other antidiabetic medications, such as metformin or insulin.


  • Promotes effective and sustained control of blood glucose levels
  • Once-daily dosing improves medication adherence and convenience
  • May help reduce the risk of long-term complications associated with diabetes
  • Well-tolerated with a favorable safety profile
  • Available in different strengths to accommodate individual dosing needs

Mechanism of Action

 Gliclazide, the active ingredient in Diamicron MR 60mg, belongs to the sulfonylurea class of antidiabetic medications. It works by stimulating the pancreatic beta cells to release more insulin, thereby increasing the levels of circulating insulin in the body. This enhanced insulin secretion helps lower blood glucose levels by facilitating the uptake of glucose into cells and reducing hepatic glucose production.


 The recommended starting dose of Diamicron MR 60mg is 30mg once daily, taken with a meal. Dosage adjustments may be necessary based on individual response and glycemic control, with a maximum daily dose of 120mg.

Side Effects

 Common side effects associated with Diamicron MR 60mg may include hypoglycemia (low blood sugar), nausea, vomiting, abdominal discomfort, and skin rash. Less common side effects may include weight gain, headache, and dizziness.


 Diamicron MR 60mg should be used with caution in patients with impaired renal or hepatic function, as dosage adjustments may be necessary. It should be avoided in patients with severe renal or hepatic impairment. Patients should inform their healthcare provider about any existing medical conditions or medications they are taking.

Important Information

 Diamicron MR 60mg may interact with certain medications, such as non-steroidal anti-inflammatory drugs (NSAIDs), beta-blockers, and certain antibiotics. Regular monitoring of blood glucose levels is essential during treatment, and hypoglycemia should be promptly addressed. Patients should follow a balanced diet and exercise regimen as recommended by their healthcare provider.

 The daily dose of DIAMICRON 60 mg may vary from one half to 2 tablets per day, i.e.from 30 to 120 mg taken orally in a single intake at breakfast time. It is recommended to swallow the dose without crushing or chewing. If a dose is forgotten, there must be no increase in the dose taken the next day. As with any hypoglycaemic agent, the dose should be adjusted according to the individual patient's metabolic response (blood glucose, HbA1c). Initial dose: The recommended starting dose is 30 mg daily (half a tablet of DIAMICRON 60 mg). If blood glucose is effectively controlled, this dose may be used for maintenance treatment. If blood glucose is not adequately controlled, the dose may be increased to 60, 90 or 120 mg daily, in successive steps. The interval between each dose increment should be at least 1 month except in patients whose blood glucose has not reduced after two weeks of treatment.


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