Diamicron MR 60mg is an extended-release formulation of gliclazide, a second-generation sulfonylurea medication. This once-daily treatment offers sustained blood glucose control for patients with type 2 diabetes mellitus, enhancing convenience and potentially improving medication adherence.
Uses
Diamicron MR 60mg is primarily used for:
- Treatment of type 2 diabetes mellitus in adults
- Management of blood glucose levels when diet, exercise, and weight reduction alone are insufficient
- Combination therapy with other antidiabetic medications like metformin or insulin
Benefits
- Provides effective and sustained control of blood glucose levels
- Improves medication adherence with convenient once-daily dosing
- May reduce the risk of long-term diabetes-related complications
- Offers a favorable safety profile and is generally well-tolerated
- Available in various strengths to accommodate individual dosing needs
How It Works
Gliclazide, the active ingredient in Diamicron MR 60mg, stimulates pancreatic beta cells to increase insulin secretion. This elevated insulin level facilitates glucose uptake by cells and reduces hepatic glucose production, effectively lowering blood glucose levels. The modified-release formulation ensures a steady release of the medication throughout the day.
Duration of Action
Diamicron MR 60mg provides 24-hour glycemic control with its extended-release formulation. The sustained release of gliclazide helps maintain stable blood glucose levels throughout the day, reducing the risk of hypoglycemic episodes and improving overall diabetes management.
Dosage
The typical starting dose is 30mg once daily, taken with breakfast. Dosage may be adjusted based on individual response and glycemic control, with a maximum daily dose of 120mg. Always follow your healthcare provider’s instructions regarding dosage adjustments.
Side Effects
Common side effects may include:
- Hypoglycemia (low blood sugar)
- Nausea and vomiting
- Abdominal discomfort
- Skin rash
Less common side effects can include weight gain, headache, and dizziness. If you experience severe or persistent side effects, contact your healthcare provider.
Warning
Use Diamicron MR 60mg with caution if you have impaired renal or hepatic function. Avoid use in cases of severe renal or hepatic impairment. Inform your healthcare provider about any existing medical conditions or medications you’re taking before starting treatment.
Pregnancy and Breastfeeding
Diamicron MR 60mg is not recommended during pregnancy or breastfeeding. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternative treatments with their healthcare provider.
Interactions
- May interact with NSAIDs, beta-blockers, and certain antibiotics
- Potential interactions with other medications that affect blood glucose levels
- Alcohol may increase the risk of hypoglycemia
Important Information
Take Diamicron MR 60mg as prescribed, usually once daily with breakfast. Regular monitoring of blood glucose levels is essential during treatment. Promptly address any signs of hypoglycemia. Maintain a balanced diet and exercise regimen as recommended by your healthcare provider. Do not adjust your dose without consulting your doctor. If you miss a dose, take it as soon as you remember, but skip it if it’s almost time for your next dose. Never double up on doses to make up for a missed one.
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