Predicure Tablet 5mg is a corticosteroid medication with Prednisolone as its active ingredient. It effectively treats inflammatory conditions by reducing inflammation and modulating immune system activity.
Uses
Predicure Tablet 5mg treats inflammatory and autoimmune conditions including asthma, rheumatoid arthritis, inflammatory bowel disease, allergic reactions, lupus, nephrotic syndrome, and certain cancers. It also helps prevent transplant rejection.
Benefits
- Powerful anti-inflammatory action
- Rapid symptom relief
- Effective immunosuppression
- Reduces swelling and inflammation
- Alleviates inflammatory pain
- Controls autoimmune flares
- Manages acute allergic reactions
- Well-established efficacy profile
How It Works
Predicure Tablet 5mg mimics natural adrenal hormones by binding to glucocorticoid receptors in cells. This reduces inflammatory chemical production and decreases immune cell activity throughout the body.
Duration of Action
Effects begin 1-2 hours after administration with anti-inflammatory benefits lasting 24-36 hours per dose. Biological half-life ranges from 12-36 hours.
Dosage
Condition | Recommended Dosage | Frequency |
---|---|---|
Acute conditions | 20-60mg | Once daily |
Chronic conditions | 5-15mg | Daily/alternate days |
Children | 0.5-2mg/kg | Once or divided |
Maintenance | 2.5-10mg | Daily/alternate days |
Warnings
Never stop taking abruptly after prolonged use. Long-term use may cause osteoporosis, diabetes, increased infection risk, and adrenal suppression. Contraindicated in untreated infections and systemic fungal infections.
Side Effects
Common effects include increased appetite, fluid retention, mood changes, insomnia, weight gain, high blood pressure, muscle weakness, thin skin, easy bruising, and increased infection risk.
Pregnancy and Breastfeeding
Use during pregnancy only if benefits outweigh risks. Prednisolone passes into breast milk. Consult healthcare provider before use while pregnant or breastfeeding.
Interactions
- NSAIDs (increased bleeding risk)
- Anticoagulants (altered effectiveness)
- Antidiabetic medications (reduced efficacy)
- CYP3A4 inhibitors/inducers (altered levels)
- Live vaccines (compromised response)
- Diuretics (electrolyte imbalances)
- Digoxin (increased toxicity risk)
Precautions
Take exactly as prescribed. Take with food to minimize stomach irritation. Carry medical identification indicating corticosteroid use. Regular monitoring of blood pressure, glucose, and bone density recommended during long-term therapy.
Important Information
Use Predicure Tablet 5mg at the lowest effective dose for the shortest duration possible. Follow tapering schedules when discontinuing. Report new symptoms promptly as this medication may mask signs of infection.
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Customer questions & answers
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Could predicure causes ear buzzling
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A
Hello Mr Okolo,
Yes, Predicure (Prednisolone) can sometimes cause side effects like ear buzzing (tinnitus), though it is not very common. If the buzzing persists or worsens, it’s best to speak with a doctor for proper evaluation
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