Pyrantrin is a renowned brand of pyrantel pamoate, a highly effective anthelmintic medication designed to expel a wide range of intestinal worms. With its broad-spectrum activity, Pyrantrin effectively targets and treats various types of gastrointestinal parasites commonly found in infestations, making it suitable for combating single or mixed-worm infestations.
Uses
Pyrantrin is used to treat various types of intestinal worm infestations, including:
- Enterobius vermicularis (pinworm or threadworm)
- Ascaris lumbricoides (roundworm)
- Ancylostoma duodenale (hookworm)
- Necator americanus (hookworm)
- Trichostrongylus colubriformis and orientalis
Benefits
- Effectively expels a wide range of intestinal worms
- Suitable for treating single or mixed worm infestations
- Provides relief from symptoms associated with worm infestations
Dosage
The dosage of Pyrantrin (pyrantel pamoate) is typically a single dose, administered orally. The recommended dosage is based on the patient’s age and weight:
| Age | Dosage (Single) |
|---|---|
| 6 months – 2 years | 2.5 ml |
| 2 – 6 years | 5 ml |
| 6 – 12 years | 10 ml |
| 12 years & above | 12.5 ml |
| Large Adults | 15 ml |
The general guideline is 10 mg of the base per kilogram of the patient’s body weight, administered as a single dose.
Mechanism of Action
Pyrantel pamoate, the active ingredient in Pyrantrin, works by causing paralysis and subsequent expulsion of the intestinal worms from the body. It acts on the neuromuscular junction of the worms, leading to their immobilization and eventual elimination through the feces.
Side Effects
Common side effects of Pyrantrin may include nausea, vomiting, abdominal pain, and diarrhea. These side effects are usually mild and temporary.
Warnings
- Pyrantrin should not be used in patients with known hypersensitivity to pyrantel pamoate or any of its components.
- Caution should be exercised in patients with liver or kidney impairment, as dosage adjustments may be necessary.
Important Information
- Follow the dosage instructions provided by your healthcare provider.
- Complete the full course of treatment as prescribed, even if symptoms improve.
- Seek medical attention if severe or persistent side effects occur.
- Practice good hygiene and sanitation to prevent re-infestation.
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