Pyrantrin Syrup is a renowned brand of pyrantel pamoate, a highly effective anthelmintic medication designed to expel a wide range of intestinal worms. With its broad-spectrum activity, Pyrantrin effectively targets and treats various types of gastrointestinal parasites commonly found in infestations, making it suitable for combating single or mixed-worm infestations.
Uses
Pyrantrin Syrup is used to treat various types of intestinal worm infestations, including:
- Enterobius vermicularis (pinworm or threadworm)
- Ascaris lumbricoides (roundworm)
- Ancylostoma duodenale (hookworm)
- Necator americanus (hookworm)
- Trichostrongylus colubriformis and orientalis
Benefits
- Effectively expels a wide range of intestinal worms
- Suitable for treating single or mixed worm infestations
- Provides relief from symptoms associated with worm infestations
- Single-dose treatment in most cases
- Well-tolerated by most patients
- Rapidly eliminates parasitic infections
- High cure rate for targeted parasites
- Easy-to-administer oral suspension
How It Works
Pyrantrin Suspension works by acting on the neuromuscular junction of intestinal worms. The active ingredient, pyrantel pamoate, causes depolarization of worm muscle cells, leading to spastic paralysis. This immobilizes the parasites, preventing them from maintaining their position in the intestine, resulting in their elimination through normal bowel movements.
Duration of Action
The medication begins working within 2-3 hours of administration. Maximum concentration in the intestine is achieved within 1-3 hours. The paralytic effect on worms occurs rapidly, with complete elimination typically occurring within 24-72 hours after administration.
Dosage
Age | Dosage (Single) | Administration |
---|---|---|
6 months – 2 years | 2.5 ml | Once |
2 – 6 years | 5 ml | Once |
6 – 12 years | 10 ml | Once |
12 years & above | 12.5 ml | Once |
Large Adults | 15 ml | Once |
Warnings
Pyrantrin Syrup should not be used in patients with known hypersensitivity to pyrantel pamoate or any of its components. Caution should be exercised in patients with liver or kidney impairment, as dosage adjustments may be necessary. Not recommended for children under 6 months unless directed by a healthcare professional.
Side Effects
Common side effects of Pyrantrin suspension may include nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, and drowsiness. These side effects are usually mild and temporary, resolving without intervention within 24-48 hours after administration.
Pregnancy and Breastfeeding
Pyrantrin Syrup should be used during pregnancy only when clearly needed and when potential benefits outweigh potential risks. It is not known whether pyrantel pamoate is excreted in human milk. Caution should be exercised when administering to nursing mothers.
Interactions
- Piperazine (antagonistic effect)
- Theophylline (increased theophylline levels)
- Chloroquine (potential decreased effectiveness)
- Other anthelmintic medications (potential additive effects)
- Certain laxatives (may reduce absorption)
Precautions
Take Pyrantrin exactly as prescribed. Shake suspension well before measuring. May be taken with or without food. Treat all household members simultaneously to prevent reinfection. Maintain proper hygiene practices including thorough handwashing. Wash bedding and clothing in hot water to kill eggs and prevent reinfection.
Important Information
Follow the dosage instructions provided by your healthcare provider. Complete the full course of treatment as prescribed, even if symptoms improve. Seek medical attention if severe or persistent side effects occur. Practice good hygiene and sanitation to prevent re-infestation.
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