Refucil Suspension contains griseofulvin, an antifungal medication used to treat various fungal infections of the skin, hair, and nails. This oral suspension formulation offers improved absorption and is particularly suitable for patients who have difficulty swallowing tablets.
Uses
Refucil Suspension treats fungal infections of the skin, scalp, hair, and nails, including ringworm, athlete’s foot, jock itch, and fungal nail infections. It’s particularly effective against dermatophyte fungi and systemic infections that topical treatments cannot reach effectively.
Benefits
- Effectively treats deep-seated fungal infections
- Penetrates hair shafts and nail beds for complete treatment
- Available in liquid form for easier administration
- Prevents spread of fungal infections to others
- Treats infections resistant to topical antifungals
- Reduces itching, scaling, and inflammation
- Prevents recurrence when used as directed
- Safe for long-term use under medical supervision
- Suitable for treating extensive fungal infections
How It Works
Griseofulvin works by binding to keratin in newly formed skin cells, making them resistant to fungal invasion. It disrupts fungal cell division by interfering with microtubule formation, ultimately stopping fungal growth. The medication concentrates in skin, hair, and nail tissue, providing targeted antifungal action.
Dosage
Patient Weight | Pediatric Dosage | Adult Dosage |
---|---|---|
15-25 kg | 5-10 ml daily | N/A |
25-35 kg | 10-15 ml daily | N/A |
Adults | N/A | 15-20 ml daily |
Take Refucil Suspension with food or milk to enhance absorption. Shake well before each use. Treatment duration varies from 4-12 weeks depending on infection type.
Duration of Action
Refucil Suspension begins working within days of starting treatment, though visible improvement may take 2-4 weeks. Hair infections typically require 4-6 weeks of treatment, while nail infections may need 6-12 months. The medication remains active in treated tissues for weeks after discontinuation.
Side Effects
Common side effects include mild headache, nausea, vomiting, and diarrhea. Some patients experience dizziness, fatigue, or skin rash. Rare but serious effects include severe allergic reactions, liver problems, or blood disorders. Most side effects are mild and resolve during treatment.
Warning
Refucil Suspension may cause photosensitivity, increasing sunburn risk. Avoid prolonged sun exposure and use sunscreen. Can reduce effectiveness of oral contraceptives. May interact with alcohol, causing flushing and rapid heartbeat. Discontinue and consult doctor if severe skin reactions, persistent nausea, or yellowing of skin occurs.
Pregnancy and Breastfeeding
Refucil Suspension is contraindicated during pregnancy due to potential birth defects. Women of childbearing age should use effective contraception during treatment and for one month after completion. The medication passes into breast milk, so breastfeeding is not recommended during treatment.
Interaction
- Reduces effectiveness of oral contraceptives and warfarin
- May increase effects of alcohol, causing unpleasant reactions
- Potential interaction with cyclosporine, reducing its effectiveness
- May interfere with certain laboratory tests
- Possible interaction with phenobarbital, reducing Griseofulvin levels
- Could affect metabolism of some medications processed by liver
Precaution
Use with caution in patients with liver disease, lupus, or porphyria. Regular liver function monitoring may be required during prolonged treatment. Avoid in patients with known hypersensitivity to Griseofulvin. Complete the full course even if symptoms improve to prevent recurrence.
Important Information
Refucil Suspension requires prescription and medical supervision. Store at room temperature, away from light and moisture. Shake well before each dose. Treatment duration depends on infection location and severity. Good hygiene practices help prevent reinfection. Inform all healthcare providers about Refucil use before any medical procedures or new medications.
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