If Ordered Today We Estimate Delivery By 21, April 2025Reludrine Proguanil Tablet x10
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Reludrine contains Proguanil, a medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria in both adult and children
₦20,000.00
Buy NowReludrine contains proguanil hydrochloride, a specialized antimalarial agent that effectively prevents and treats malaria. This strategic formulation works by targeting specific metabolic pathways in malarial parasites, providing reliable protection against Plasmodium infections.
Uses
Reludrine serves two primary functions: malaria prevention for travelers to endemic regions and treatment of acute uncomplicated malaria. It’s particularly effective when combined with other antimalarial medications for comprehensive protection.
Benefits
- Effective malaria prevention
- Reliable parasite elimination
- Enhanced treatment efficacy
- Reduced resistance development
- Convenient once-daily dosing
- Well-established safety profile
- Suitable for long-term prophylaxis
- Compatible with other antimalarials
How It Works
Reludrine functions by inhibiting dihydrofolate reductase in malarial parasites, disrupting their folate synthesis pathway. This interference prevents parasite DNA replication and protein synthesis, effectively halting their growth and reproduction.
Duration of Action
Prophylactic protection begins after 1-2 days of use. For optimal prevention, start medication 1-2 weeks before entering malaria-risk areas. Continue for 4 weeks after leaving endemic regions.
Dosage
| Use Case | Daily Dose | Timing | Duration |
|---|---|---|---|
| Prevention | 200mg | Once daily | Throughout exposure |
| Treatment | As prescribed | Once daily | As directed |
| Children | Weight-based | Once daily | As directed |
Side Effects
Generally well-tolerated with minimal adverse effects. Initial gastrointestinal adjustments may occur but typically resolve within days.
Warning
Discontinue and seek immediate medical attention if experiencing severe allergic reactions, unusual bleeding, or persistent fever. Regular monitoring required during treatment.
Pregnancy and Breastfeeding
Safety assessment required for pregnant women. Benefits often outweigh risks in malaria-endemic areas. Discuss with healthcare provider for individualized recommendations.
Interactions
- May interact with warfarin
- Potential effects with folate supplements
- Consider spacing with antacids
- Some antibiotics may affect efficacy
Precautions
Take with food to minimize stomach upset. Maintain consistent dosing schedule. Complete full course of treatment. Monitor for breakthrough symptoms.
Important Information
Store at room temperature (20-25°C) in original container. Protect from moisture and light. Start prophylaxis before entering malaria-risk areas. Continue for prescribed duration after leaving endemic regions. Report unusual symptoms promptly. Keep detailed travel record. Carry medical documentation when traveling. Regular check-ups recommended during long-term use.
| Category | Dosage Instructions |
|---|---|
| Adults and Children >14 years | 200 mg once daily |
| Children 9-14 years | 100 mg once daily |
| Children 5-8 years | 50 mg once daily |
| Children <5 years | 25 mg once daily |
How to Use
- Take the tablet with or immediately after food to enhance absorption.
- Swallow the tablet with a full glass of water.
- Take the medication at the same time each day for consistent blood levels.
Special Notes
- Proguanil is primarily used for malaria prevention.
- Start taking the tablet 1-2 days before entering a malaria-prone area and continue for 7 days after leaving the area.
- Not suitable for individuals with severe renal impairment without medical advice.
- Store the medication in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
Frequently Bought Together
Price for all
₦26,500.00
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