Grutha Fort 480mg is a fixed-dose combination antimalarial medication containing two active ingredients – artemether and lumefantrine. It belongs to the artemisinin-based combination therapy (ACT) class of drugs recommended for treating uncomplicated malaria.
Uses
Grutha Fort 480mg is primarily used for:
- Treatment of acute uncomplicated Plasmodium falciparum malaria
- Treatment of chloroquine-resistant malaria strains
- Malaria chemoprophylaxis in high-risk areas
Benefits
The key benefits of taking Grutha Fort include:
- Rapidly clears Plasmodium falciparum malaria infection
- Effective against multi-drug resistant malaria strains
- Prevents complications associated with severe malaria
- Combination therapy reduces risk of parasite resistance
- Well-tolerated with a convenient dosing regimen
Mechanism of Action
Artemether is a potent and rapidly acting antimalarial derived from artemisinin. Lumefantrine is longer-acting and prevents recrudescence. The combination provides an initial rapid reduction followed by complete clearance of malaria parasites.
Dosage
For adults: 1 tablet as a single initial dose, then 1 capsule after 8 hours, and then twice daily (morning and evening) for the following two days (total course of 6 capsules). For children based on weight. Administer with food/milk to enhance absorption. Complete the full course as prescribed.
Side Effects
Common side effects include headache, dizziness, nausea, vomiting, abdominal pain, loss of appetite, and palpitations. Most are mild and self-limiting. Seek medical advice for persistent symptoms.Warnings
Do not use if allergic to artemether, lumefantrine, or related compounds. Use with caution in severe malaria and hepatic/renal impairment. Avoid in the first trimester of pregnancy unless essential.
Important Information
Take with food/milky drinks to maximize absorption. Complete full course for effective malaria treatment. Do not stop midway even if feeling better. Report any persisting fever/chills to your doctor.
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