SamJones Tamsulosin XL 400mcg x30

SamJones Tamsulosin XL 400mcg is an extended-release formulation of Tamsulosin hydrochloride. This alpha-1 adrenergic receptor antagonist effectively treats benign prostatic hyperplasia (BPH) symptoms by relaxing smooth muscles in the prostate and bladder neck.

Uses

SamJones Tamsulosin XL treats symptoms of benign prostatic hyperplasia including difficulty urinating, weak urine stream, frequent urination, and incomplete bladder emptying. It may also be used off-label to help pass kidney stones by relaxing ureteral smooth muscle.

Benefits

• Improves urine flow and reduces urinary hesitancy
• Decreases frequency of nighttime urination
• Reduces feeling of incomplete bladder emptying
• Alleviates urgency and straining during urination
• Provides 24-hour symptom control with once-daily dosing
• Improves quality of life in BPH patients
• Reduces risk of acute urinary retention
• May help with kidney stone passage
• Well-tolerated with minimal systemic effects

How It Works

SamJones Tamsulosin XL selectively blocks alpha-1A adrenergic receptors in the prostate and bladder neck smooth muscle. This blockade causes muscle relaxation, reducing urethral resistance and improving urine flow. The extended-release formulation provides consistent drug levels throughout the day.

Dosage

Take SamJones Tamsulosin XL approximately 30 minutes after the same meal each day. Swallow whole; do not crush, chew, or open capsules.

Duration of Action

SamJones Tamsulosin XL begins working within hours of administration, with peak plasma concentrations reached in 4-6 hours. The extended-release formulation provides sustained effects for 24 hours. Significant symptom improvement typically occurs within 2-4 weeks of regular use.

Side Effects

Common side effects include dizziness, headache, and runny nose. Some patients experience fatigue, back pain, or mild gastrointestinal upset. Orthostatic hypotension may occur, especially when standing quickly. Retrograde ejaculation is possible but usually reversible upon discontinuation.

Warning

SamJones Tamsulosin XL may cause dizziness or fainting, particularly after the first dose or when resuming treatment. Avoid driving or operating machinery until response is known. Inform ophthalmologist about use before cataract surgery as it may cause intraoperative floppy iris syndrome.

Pregnancy and Breastfeeding

SamJones Tamsulosin XL is not indicated for use in women. It’s specifically designed for male patients with benign prostatic hyperplasia. No data exists regarding use during pregnancy or breastfeeding as it’s not intended for female use.

Interaction

• May enhance hypotensive effects of antihypertensive medications
• Potential interaction with other alpha-blockers causing excessive blood pressure reduction
• CYP3A4 inhibitors may increase tamsulosin levels
• Warfarin effects may be enhanced requiring monitoring
• Cimetidine may increase tamsulosin concentrations
• PDE5 inhibitors may cause additive hypotensive effects

Precaution

Use with caution in patients with severe liver or kidney impairment. Monitor blood pressure regularly, especially in elderly patients. Avoid sudden position changes to prevent dizziness. Inform all healthcare providers about SamJones Tamsulosin XL use before medical procedures, particularly eye surgery.

Important Information

SamJones Tamsulosin XL is for male patients only and should not be used by women or children. Take consistently at the same time each day for optimal effectiveness. Don’t stop taking suddenly without consulting your doctor. If you miss a dose for several days, restart at the lowest dose. Store at room temperature away from moisture and heat. Regular follow-up appointments are necessary to monitor treatment response.