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Senamet Tablet (Carbidopa/Levodopa) x50

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Senamet Tablet is used for the treatment of Parkinson’s disease symptoms, and controlling motor fluctuations in advanced Parkinson’s disease.

21,000.00

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Availability: In Stock
SKU:SEN872

Senamet Tablet is a powerful medication combining carbidopa and levodopa, specifically designed to manage Parkinson’s disease symptoms. This dual-action formula effectively increases dopamine levels in the brain, helping to control motor symptoms and improve quality of life for patients with Parkinson’s disease.

Uses

Senamet is primarily used for:

  • Managing motor symptoms of Parkinson’s disease
  • Treating Parkinson-like symptoms caused by certain medications
  • Managing some forms of parkinsonism

Benefits

  • Reduces tremors and muscle stiffness
  • Improves movement and muscle control
  • Enhances overall mobility and flexibility
  • Decreases “off” time in Parkinson’s patients
  • Improves ability to perform daily activities
  • May reduce depression associated with Parkinson’s disease

How It Works

Levodopa in Senamet is converted to dopamine in the brain, replenishing depleted levels of this crucial neurotransmitter. Carbidopa prevents the premature conversion of levodopa outside the brain, allowing more levodopa to reach the brain and enhancing its effectiveness while reducing side effects.

Duration of Action

The effects of Senamet Tablet typically begin within 30-60 minutes after ingestion. The duration of action varies but usually lasts 4-6 hours per dose. As the disease progresses, the duration may shorten, requiring more frequent dosing.

Dosage

Dosage is highly individualized and should be determined by a healthcare professional. Typically, treatment starts with a low dose and is gradually increased. Most patients take Senamet 3-4 times daily, with dosages ranging from 25/100 mg to 50/200 mg (carbidopa/levodopa) per dose.

Side Effects

Common side effects may include nausea, dizziness, headache, and dry mouth. More serious side effects can include involuntary movements (dyskinesia), hallucinations, and sudden onset of sleep. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Warning

Senamet Tablet should not be abruptly discontinued as it may lead to a dangerous condition called neuroleptic malignant syndrome. Patients with narrow-angle glaucoma, severe heart disease, or a history of melanoma should use Senamet with caution. Always inform your doctor about any pre-existing conditions before starting treatment.

Pregnancy and Breastfeeding

The safety of Senamet during pregnancy and breastfeeding has not been established. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using this medication.

Interactions

  • May interact with certain antidepressants, particularly MAO inhibitors
  • Can interfere with the absorption of iron supplements
  • May interact with some antihypertensive medications
  • Can affect the efficacy of certain psychiatric medications

Important Information

Take Senamet as prescribed, preferably at the same times each day. It’s often recommended to take the medication with or just after meals to minimize stomach upset. If you miss a dose, take it as soon as you remember, but skip it if it’s almost time for your next dose. Regular follow-ups with your healthcare provider are essential to monitor your response to the medication and adjust the dosage as needed.

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Category Dosage Instructions
Adults (Parkinson’s Disease - Initial Therapy) Starting dose: One tablet of 25 mg Carbidopa / 100 mg Levodopa three times daily. May be increased by one tablet daily or every other day, as tolerated.
Adults (Maintenance Therapy) Maintenance dose: 70-100 mg of Carbidopa and 300-800 mg of Levodopa daily, divided into 3 or more doses, depending on the individual response and tolerance.
Adults (Advanced Parkinson’s Disease) Dosage may be increased to up to 200 mg Carbidopa / 2000 mg Levodopa daily in divided doses. Consult a doctor for precise titration and frequency adjustments.
Renal Impairment No specific dosage adjustment required, but close monitoring is advised. Consult your doctor for recommendations.
Elderly Starting with a lower dose is recommended due to possible increased sensitivity. Dosage adjustments should be done carefully based on response.
Children Not recommended in children under 18 years unless specifically prescribed by a healthcare provider.

Important Notes:

  • Senamet should be taken with or just after meals to reduce nausea, but avoid high-protein meals as they may affect Levodopa absorption.
  • Do not crush or chew the tablets unless prescribed in a dispersible form.
  • It may take several weeks to notice full benefits. Continue the medication as prescribed.
  • Do not stop taking the medication suddenly without consulting your healthcare provider, as this can lead to serious withdrawal symptoms, including a severe condition called neuroleptic malignant syndrome.
  • Side effects may include dizziness, nausea, confusion, or involuntary movements. Report any unusual side effects to your doctor immediately.

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