Tamduster Tablet (Tamsulosin) x30

Tamduster Tablet combines Tamsulosin and Dutasteride to treat benign prostatic hyperplasia (BPH). This dual-action formula provides both immediate symptom relief through alpha-blockade and long-term prostate size reduction through 5-alpha reductase inhibition.

Uses

Tamduster treats moderate to severe symptoms of benign prostatic hyperplasia in men with enlarged prostate glands. It reduces urinary frequency, urgency, weak stream, incomplete bladder emptying, and nighttime urination. The medication helps prevent BPH progression and reduces the need for prostate surgery.

Benefits

• Provides dual-action BPH treatment in one tablet
• Offers immediate relief of urinary symptoms
• Reduces prostate size over time
• Decreases risk of acute urinary retention
• Lowers likelihood of BPH-related surgery
• Improves urinary flow rate and bladder emptying
• Reduces nighttime urination frequency
• Enhances quality of life for BPH patients
• Convenient once-daily dosing

How It Works

Tamsulosin, an alpha-1 blocker, relaxes smooth muscles in the prostate and bladder neck, providing immediate improvement in urine flow. Dutasteride inhibits both type I and II 5-alpha reductase enzymes, reducing dihydrotestosterone production and gradually shrinking the prostate over months of treatment.

Dosage

Take Tamduster approximately 30 minutes after the same meal each day. Swallow whole without crushing or chewing the capsule.

Duration of Action

Tamsulosin begins improving urinary symptoms within hours to days of starting treatment. Dutasteride’s prostate-shrinking effects typically become noticeable after 3-6 months of continuous use. Maximum benefits are usually achieved after 6-12 months of regular therapy with continued improvement over time.

Side Effects

Common side effects include dizziness, decreased libido, ejaculation disorders, and erectile dysfunction. Some patients experience fatigue, nasal congestion, or breast tenderness. Orthostatic hypotension may occur, especially when standing up quickly. Most side effects are mild and may improve with continued use.

Warning

Tamduster may cause sudden drop in blood pressure, especially with the first dose or when changing positions. It can affect male fertility and sexual function. Women and children should not handle crushed or broken tablets due to risk of absorption. May increase risk of high-grade prostate cancer in some studies.

Pregnancy and Breastfeeding

Tamduster is contraindicated in women and children. Pregnant women should not handle broken or crushed tablets as Dutasteride can cause abnormalities in male fetus genitalia. The medication is absorbed through skin contact and poses significant risks to developing male fetuses.

Interaction

• May interact with other alpha-blockers causing excessive blood pressure reduction
• Possible enhanced effects with phosphodiesterase-5 inhibitors
• CYP3A4 inhibitors may increase Dutasteride levels
• May affect PSA test results, requiring interpretation adjustment
• Potential interaction with warfarin affecting blood clotting times

Precaution

Monitor blood pressure regularly, especially during initial treatment. Use caution when driving or operating machinery due to dizziness risk. Inform healthcare providers about Tamduster use before surgery, particularly cataract surgery. Regular prostate examinations and PSA monitoring are recommended during treatment.

Important Information

Tamduster requires several months for full effectiveness. Continue taking even if symptoms improve. PSA levels typically decrease by 50% after 6 months of treatment. Report any breast lumps, nipple discharge, or persistent sexual side effects. Store at room temperature away from moisture. Do not donate blood during treatment and for 6 months after discontinuation.