If Ordered Today We Estimate Delivery By 23, April 2025Uperio 100mg (Sacubitril and Valsartan) x28
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Uperio 100mg Tablet is used to treat chronic heart failure with reduced ejection fraction (HFrEF), and potentially slow the progression of heart failure.
₦70,000.00
Buy NowUperio 100mg Tablet combines Sacubitril and Valsartan, offering a novel approach to heart failure treatment. This angiotensin receptor-neprilysin inhibitor (ARNI) effectively reduces the risk of cardiovascular death and hospitalization in patients with chronic heart failure, providing a significant advancement in heart failure management.
Uses
Uperio 100mg Tablet is primarily used for- Treatment of chronic heart failure with reduced ejection fraction (HFrEF)
- Reducing the risk of cardiovascular death and hospitalization in heart failure patients
- Managing symptoms of heart failure, such as shortness of breath and fatigue
- Improving quality of life in patients with chronic heart failure
- Potentially slowing the progression of heart failure
Benefits
- Reduces risk of cardiovascular death and hospitalization
- Improves heart failure symptoms
- Enhances quality of life for heart failure patients
- May slow disease progression
- Once-daily dosing for convenient use
- Combines two effective mechanisms of action
How It Works
Sacubitril inhibits neprilysin, increasing levels of beneficial peptides that support heart function. Valsartan blocks angiotensin II receptors, relaxing blood vessels and reducing strain on the heart. This dual action provides comprehensive heart failure management.
Dosage
The usual starting dose is one tablet of Uperio 100mg twice daily. Your doctor may adjust the dose based on your response and tolerance. Take Uperio at the same time each day, with or without food.
Side Effects
Common side effects may include low blood pressure, high potassium levels, kidney problems, and cough. Most side effects are mild to moderate. Contact your doctor if side effects persist or worsen.
Warning
Do not use during pregnancy as it can harm the unborn baby. Avoid in patients with a history of angioedema. Use with caution in patients with severe kidney or liver disease. Do not take with ACE inhibitors.
Interaction
Uperio may interact with other medications. Inform your doctor about all drugs you’re taking, including:
- ACE inhibitors
- Potassium supplements or salt substitutes
- NSAIDs (like ibuprofen)
- Lithium
- Certain statins
Important Information
Regular monitoring of blood pressure, kidney function, and potassium levels is essential while taking Uperio. Follow your doctor’s instructions carefully and report any significant changes in your condition. Do not stop taking Uperio without consulting your doctor, as sudden discontinuation may worsen your heart failure symptoms.
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| Group | Initial Dose | Maintenance/Maximum Dose |
|---|---|---|
| Adults (Heart Failure) | 49 mg sacubitril/51 mg valsartan twice daily | Adjust to 97 mg sacubitril/103 mg valsartan twice daily based on tolerance and response |
| Renal Impairment (Moderate) | 24 mg sacubitril/26 mg valsartan twice daily | Adjust based on tolerance and response |
| Hepatic Impairment (Mild to Moderate) | 24 mg sacubitril/26 mg valsartan twice daily | Adjust based on tolerance and response |
- Uperio should be taken twice daily.
- Dosage adjustments may be required based on the patient's response, renal function, and hepatic function.
- Always follow the healthcare provider’s instructions.
- Regular monitoring of blood pressure and kidney function is recommended.
- Consult with a healthcare professional before starting or changing the dose of Uperio.
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Price for all
₦98,000.00
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