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Uperio 200mg (Sacubitril and Valsartan) x28

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Uperio 200mg is used for patients with chronic heart failure with reduced ejection fraction. It improves cardiovascular performance, reduces hospitalization

70,000.00

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Availability: In Stock
SKU:UPR3473

Uperio 200mg is a combination medication designed to treat heart failure, combining sacubitril and valsartan. This innovative pharmaceutical intervention targets complex cardiovascular conditions by addressing multiple physiological mechanisms to improve cardiac function and patient outcomes.

Uses

Uperio is primarily prescribed for patients with symptomatic chronic heart failure with reduced ejection fraction. It helps improve cardiovascular performance, reduce hospitalizations, and enhance overall quality of life for individuals with specific heart-related medical conditions.

Benefits

  • Reduces cardiovascular hospitalization risks
  • Improves heart failure symptoms
  • Enhances cardiac function
  • Supports long-term heart health
  • Provides dual-action cardiovascular protection
  • Reduces risk of cardiovascular mortality
  • Helps manage blood pressure
  • Supports overall cardiac performance

How It Works

Uperio combines sacubitril, a neprilysin inhibitor, and valsartan, an angiotensin receptor blocker. This unique combination works synergistically to improve cardiac function by reducing strain on the heart, promoting vasodilation, and supporting the body’s natural cardiovascular regulatory mechanisms.

Duration of Action

The medication provides continuous cardiovascular support with effects typically maintained throughout the 24-hour period. Consistent blood levels are achieved with regular daily administration as prescribed by healthcare professionals.

Dosage

Patient Category Initial Dosage Maintenance Dosage Frequency
Adults 24/26mg twice daily Up to 97/103mg twice daily Twice daily
Elderly Lower initial dosage Individualized approach As directed

Warning

Strictly follow medical prescription. Do not alter dosage without professional medical consultation. Potential risks include hypotension, hyperkalemia, and renal impairment. Regular medical monitoring is essential.

Side Effects

Potential side effects include dizziness, hypotension, kidney function changes, elevated potassium levels, and headaches. Some patients may experience more severe reactions requiring immediate medical attention.

Pregnancy and Breastfeeding

Contraindicated during pregnancy and breastfeeding. Potential significant risks to fetal development and infant health require alternative treatment approaches.

Interactions

  • Potential interactions with blood pressure medications
  • May affect potassium-sparing diuretics
  • Interactions possible with lithium-based medications
  • Potential complications with non-steroidal anti-inflammatory drugs

Precaution

Exercise extreme caution in patients with:

  • History of angioedema
  • Renal impairment
  • Hepatic dysfunction
  • Hypotension
  • Elderly patients with complex medical histories

Important Information

Uperio represents a specialized cardiovascular treatment requiring comprehensive medical supervision. Regular cardiac monitoring, kidney function tests, and blood pressure assessments are crucial during treatment.

Note: This guide provides general information about Uperio 200mg. Individual medical needs vary, and consultation with a healthcare professional is essential for proper cardiovascular management.

Product Image Highlights

Uperio 200mg
Uperio Tablet
Uperio 200mg Tablet
Uperio

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Category Dosage Instructions
Initial Dose 50mg or 100mg twice daily, based on previous ACE inhibitor/ARB dose and patient tolerance.
Maintenance Dose 200mg twice daily (recommended target dose).
Patients Switching from ACE Inhibitors Discontinue ACE inhibitors 36 hours before starting Uperio to reduce the risk of angioedema.
Renal Impairment Moderate: Start with 50mg twice daily. Severe: Use with caution.
Hepatic Impairment Mild: No adjustment needed. Moderate: Start with 50mg twice daily. Severe: Use is not recommended.
Elderly Patients Dose adjustments may not be necessary unless renal or hepatic impairment is present.

Important Information

  • Administration: Take orally with or without food. Swallow tablets whole.
  • Monitoring: Regularly monitor blood pressure, renal function, and potassium levels.
  • Warning: Avoid in pregnancy or with a history of angioedema.

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