Zolat Suspension contains Albendazole, a broad-spectrum anthelmintic medication effective against various intestinal parasites. This oral suspension formulation is particularly suitable for children and adults who have difficulty swallowing tablets.
Uses
Zolat Suspension treats infections caused by intestinal worms including roundworms, hookworms, whipworms, threadworms, and tapeworms. It’s also effective against hydatid disease, neurocysticercosis, and giardiasis. The suspension format ensures accurate dosing for children based on weight.
Benefits
- Broad-spectrum activity against multiple parasites
- Single-dose treatment for most common worm infections
- Palatable suspension form improves compliance in children
- Effectively eliminates both mature worms and larvae
- Reduces risk of reinfection when used in community treatment
- Helps prevent complications of chronic parasitic infections
- Can be used prophylactically in high-risk settings
- Improves nutritional status by eliminating parasitic burden
- Cost-effective treatment for endemic areas
How It Works
Albendazole works by binding to parasite tubulin, inhibiting glucose uptake and preventing microtubule formation. This disrupts the parasite’s energy metabolism and immobilizes worms, eventually leading to their death. The medication affects both adult parasites and their eggs, providing comprehensive treatment.
Dosage
Condition | Age/Weight | Dosage |
---|---|---|
Common roundworms | Children (>2 years) | 10 ml (400 mg) single dose |
Common roundworms | Adults | 20 ml (800 mg) single dose |
Hydatid disease | Adults & children >6 years | 10-15 ml daily for 28 days |
Shake well before measuring. Take with food, preferably fatty meals, to enhance absorption.
Duration of Action
Zolat Suspension begins working within hours after administration. For common intestinal worms, a single dose effectively eliminates parasites within 3 days. For tissue parasites like hydatid cysts, the longer treatment course maintains therapeutic levels for continuous action against persistent cysts.
Side Effects
Most patients tolerate Zolat well. Common side effects include mild abdominal pain, nausea, vomiting, or dizziness. Temporary hair loss may occur with prolonged treatment courses. Serious side effects are rare but may include severe skin reactions or liver problems, especially with extended use.
Warning
Do not use in children under 1 year of age. Patients with liver disease require dosage adjustment and monitoring. High-dose, long-term therapy requires regular blood count and liver function monitoring. Rare cases of bone marrow suppression have been reported with extended therapy.
Pregnancy and Breastfeeding
Zolat is contraindicated during pregnancy, especially the first trimester, due to potential embryotoxic effects. Use during pregnancy only when benefit clearly outweighs risk. Limited data suggests minimal risk during breastfeeding, but consult healthcare provider before use.
Interaction
- May increase levels of certain anti-seizure medications
- Cimetidine may increase albendazole concentration
- Dexamethasone increases levels in neurocysticercosis treatment
- Fatty foods significantly increase absorption
- May alter effectiveness of warfarin anticoagulation
Precaution
Take exactly as prescribed. Complete full course even after symptoms improve. Maintain good hygiene to prevent reinfection. Treat all household members simultaneously in cases of pinworm or threadworm to prevent cross-infection. Children require supervision during administration to ensure correct dosage.
Important Information
Zolat Suspension treats worm infections but doesn’t prevent future infections without proper hygiene. Stool examination may be recommended 2-3 weeks after treatment to confirm clearance. Store suspension at room temperature, shake well before each use, and use within 24 months of manufacturing date. Treatment of severe neurocysticercosis should include hospitalization and anti-inflammatory medications.
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