Aldactone 25mg contains spironolactone, a potassium-sparing diuretic and aldosterone antagonist. This prescription medication effectively manages fluid retention while maintaining potassium balance, making it valuable for treating various cardiovascular and endocrine conditions.
Uses
Aldactone is prescribed for treating fluid retention (edema) associated with heart failure, liver cirrhosis, and nephrotic syndrome. It’s also effective in managing high blood pressure, primary hyperaldosteronism (Conn’s syndrome), and low potassium levels. Additionally, it’s used off-label for treating hormone-related conditions.
Benefits
- Controls fluid retention effectively
- Maintains potassium balance
- Helps manage blood pressure
- Treats primary hyperaldosteronism
- Reduces ascites in liver disease
- Supports heart failure management
- Treats resistant hypertension
- Minimizes potassium loss
How It Works
Spironolactone blocks aldosterone receptors in the kidneys, preventing sodium and water reabsorption while preserving potassium. This unique mechanism helps eliminate excess fluid from the body while maintaining essential electrolyte balance.
Duration of Action
Effects typically begin within 2-3 days, with maximum benefit achieved within 2 weeks. The full therapeutic effect for blood pressure control may take several weeks. Regular monitoring ensures optimal therapeutic response.
Dosage
Starting dose: 25-100mg daily Maintenance dose: Individualized based on response Frequency: Single or divided doses Maximum daily dose: 400mg for severe cases Take with food to improve absorption
Side Effects
Common side effects include increased potassium levels, breast tenderness, irregular menstruation, and mild nausea. Most side effects are dose-dependent and reversible.
Warning
Regular monitoring of potassium, sodium, and kidney function is essential. Discontinue if hyperkalemia develops. Avoid salt substitutes containing potassium. Use cautiously with ACE inhibitors or ARBs due to increased hyperkalemia risk.
Pregnancy and Breastfeeding
Aldactone 25mg is not recommended during pregnancy due to potential feminization of male fetuses. Use during breastfeeding should be discussed with healthcare provider as small amounts may pass into breast milk.
Interactions
- ACE inhibitors increase hyperkalemia risk
- NSAIDs may reduce effectiveness
- Potassium supplements should be avoided
- Lithium levels may be affected
- Digoxin levels may be altered
Important Information
Store Aldactone 25mg at room temperature away from moisture and heat. Monitor blood pressure and electrolytes regularly. Report unusual symptoms promptly. Don’t stop medication abruptly without medical advice. Maintain consistent dietary habits while taking this medication. Follow low-salt diet as recommended. Avoid excessive potassium intake through diet or supplements.
Reviews
There are no reviews yet.