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Natrixam 1.5/5mg

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Natrixam 1.5/5mg is a combination medication that contains indapamide and amlodipine. It is used to treat high blood pressure (hypertension)


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Natrixam 1.5/5mg tablets contain a lower dose combination of indapamide 1.5mg, a diuretic, and amlodipine 5mg, a calcium channel blocker, for managing hypertension in patients who require multi-drug therapy for adequate blood pressure control.

Natrixam 1.5/5mg provides dual complementary antihypertensive effects by promoting sodium and water excretion while relaxing blood vessels. It is indicated when monotherapy alone has not reduced elevated blood pressure sufficiently.


  • Achieves better BP lowering than individual components
  • Lowers cardiovascular disease risk
  • Once daily oral administration
  • Well tolerated with minimal side effects
  • Appropriate for Stage 1 and some Stage 2 hypertensives

Mechanism of Action

Indapamide reduces blood volume by increasing urinary sodium excretion while amlodipine causes vasodilation by blocking calcium channels in vascular smooth muscle.


Adults take 1 tablet orally each morning, ideally at the same time daily. Dosage may be adjusted based on individual blood pressure monitoring.


Promptly report signs of electrolyte imbalance, gout flares or dangerously low BP. Requires close medical supervision.

Important Information
Inform your doctor of any kidney/liver disorders or heart conditions before use. Routine blood work helps monitor for side effects on kidney function and electrolyte levels.

The recommended starting dose for Natrixam is 1.5mg/5mg is 1 tablet daily. This dose should be taken once daily in the morning with or without food. The dosage of Natrixam may be adjusted by your healthcare provider based on your individual blood pressure response and tolerability. The maximum recommended dose is 3mg/10mg per day. It is important to take Natrixam exactly as prescribed by your healthcare provider. Do not change the dose or stop taking the medication without consulting your healthcare provider first. If you miss a dose, take it as soon as you remember. If it is close to the time for the next dose, skip the missed dose and resume your normal dosing schedule. Do not take a double dose to make up for a missed one.


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