Axerem 250mg Tablet contains Azithromycin, a macrolide antibiotic effective against various bacterial infections. This broad-spectrum antibiotic treats respiratory tract infections, skin infections, ear infections, and sexually transmitted diseases with convenient dosing schedules.
Uses
Axerem 250mg treats bacterial infections including pneumonia, bronchitis, sinusitis, throat infections, skin and soft tissue infections, ear infections, and certain sexually transmitted infections. It’s effective against many gram-positive and gram-negative bacteria commonly causing respiratory and skin infections.
Benefits
- Provides broad-spectrum antibacterial coverage
- Offers convenient once-daily dosing regimen
- Achieves high tissue concentration levels
- Requires shorter treatment courses than many antibiotics
- Well-tolerated with fewer gastrointestinal side effects
- Effective against atypical bacterial pathogens
- Reduces bacterial resistance development risk
- Suitable for patients allergic to penicillin
- Maintains effectiveness against resistant strains
How It Works
Axerem works by binding to the 50S ribosomal subunit of bacteria, inhibiting protein synthesis essential for bacterial growth and reproduction. This bacteriostatic action prevents bacteria from multiplying, allowing the body’s immune system to eliminate the infection effectively.
Dosage
| Infection Type | Standard Dosage | Treatment Duration |
|---|---|---|
| Respiratory Infections | 500mg once daily | 3 days |
| Skin Infections | 500mg once daily | 5 days |
| STDs (Chlamydia) | 1000mg single dose | 1 day |
Take Axerem on an empty stomach, at least 1 hour before or 2 hours after meals for optimal absorption.
Duration of Action
Axerem begins working within hours of administration, with bacterial growth inhibition starting immediately. Clinical improvement typically occurs within 24-48 hours. The medication maintains therapeutic levels for several days after the last dose due to its long half-life and tissue accumulation.
Side Effects
Common side effects include mild gastrointestinal upset such as nausea, diarrhea, or abdominal discomfort. Some patients may experience headache, dizziness, or temporary hearing changes. Rare but serious effects include severe allergic reactions, liver problems, or heart rhythm disturbances.
Warning
Complete the full prescribed course even if symptoms improve early. Axerem may cause serious heart rhythm problems in some patients. Avoid in those with known QT prolongation or taking medications affecting heart rhythm. Seek immediate medical attention for severe diarrhea, chest pain, or allergic reactions.
Pregnancy and Breastfeeding
Axerem is generally considered safe during pregnancy when benefits outweigh risks. It’s often preferred over other antibiotics for treating infections in pregnant women. Small amounts pass into breast milk, but it’s usually compatible with breastfeeding under medical supervision.
Interaction
- May increase levels of certain blood thinners like warfarin
- Possible interaction with heart rhythm medications
- May affect absorption when taken with antacids containing aluminum or magnesium
- Potential interaction with ergot alkaloids
- May increase side effects of certain cholesterol medications
- Possible reduced effectiveness with some antiseizure medications
Precaution
Use with caution in patients with liver disease, kidney impairment, or heart rhythm disorders. Inform healthcare provider about history of allergic reactions to macrolide antibiotics. Monitor for signs of antibiotic-associated diarrhea. Avoid unnecessary sun exposure as photosensitivity may occur.
Important Information
Axerem is prescription-only and should be used exactly as directed. Do not share with others or save leftover tablets for future infections. Misuse contributes to antibiotic resistance. Store at room temperature away from moisture and heat. Report any unusual symptoms or lack of improvement to your healthcare provider promptly.
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