Crescent Simvastatin 10mg Tablet x28

Crescent Simvastatin 10mg is a prescription medication containing simvastatin, a member of the statin class of drugs. It’s primarily used to lower cholesterol levels and reduce the risk of cardiovascular events. This low-dose formulation is often prescribed as an initial or maintenance dose for patients requiring cholesterol management.

Uses

Crescent Simvastatin 10mg is used to:

• Lower LDL (bad) cholesterol and triglycerides
• Raise HDL (good) cholesterol
• Reduce the risk of heart attack, stroke, and other cardiovascular events
• Treat primary hypercholesterolemia and mixed dyslipidemia
• Prevent cardiovascular disease in high-risk patients

Benefits

• Effectively lowers LDL cholesterol and triglycerides
• Raises HDL cholesterol levels significantly
• Reduces risk of cardiovascular events and complications
• Well-tolerated at low therapeutic doses
• Suitable for primary and secondary prevention strategies
• May slow atherosclerosis progression
• Cost-effective treatment for hyperlipidemia
• Proven long-term safety profile
• Compatible with lifestyle modifications

How It Works

Crescent Simvastatin inhibits HMG-CoA reductase, a key liver enzyme responsible for cholesterol production. This inhibition increases LDL cholesterol removal from bloodstream while reducing cholesterol synthesis, resulting in significantly lower blood cholesterol levels and improved cardiovascular risk profile.

Dosage

Take in the evening with or without food. Dosage adjustments based on individual response and cholesterol targets.

Duration of Action

Crescent Simvastatin begins working within hours of administration, with peak cholesterol-lowering effects occurring within 2-4 weeks of regular use. Maximum therapeutic benefits are typically achieved after 4-6 weeks of consistent daily dosing. Effects persist for 24 hours after each dose.

Side Effects

Common side effects include muscle pain, headache, nausea, abdominal discomfort, and constipation. Most side effects are mild and resolve with continued use. Rare but serious effects include liver dysfunction and rhabdomyolysis, requiring immediate medical attention if muscle symptoms occur.

Warning

Crescent Simvastatin can cause serious muscle problems including rhabdomyolysis in rare cases. Report unexplained muscle pain, tenderness, or weakness immediately. Avoid grapefruit products during treatment. Contraindicated in pregnancy and active liver disease. Regular monitoring recommended.

Pregnancy and Breastfeeding

Crescent Simvastatin is contraindicated during pregnancy due to potential fetal harm. Women of childbearing age should use effective contraception during treatment. The medication passes into breast milk, so breastfeeding mothers should discontinue nursing or the medication based on medical advice.

Interaction

• Strong CYP3A4 inhibitors increase simvastatin levels significantly
• Certain antifungals and antibiotics enhance muscle toxicity risk
• Fibrates and niacin increase rhabdomyolysis risk
• Cyclosporine significantly increases drug concentration
• Amiodarone and calcium channel blockers require dose limitations
• Warfarin effects may be enhanced requiring monitoring

Precaution

Use cautiously in patients with liver disease, kidney impairment, or history of muscle disorders. Elderly patients require lower starting doses. Discontinue before major surgery. Monitor liver function and creatine kinase levels regularly. Avoid excessive alcohol consumption during treatment.

Important Information

Take Crescent Simvastatin 10mg exactly as prescribed. Regular blood tests may be required to monitor cholesterol levels and liver function. This medication is most effective when combined with a healthy diet and regular exercise. If you experience any symptoms of liver problems (e.g., unusual fatigue, loss of appetite, right upper abdominal discomfort, dark urine, or yellowing of the skin or eyes), contact your healthcare provider immediately.