Donyflu Tablet 200mg (Fluconazole) x10
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Donyflu Tablet 200mg treats numerous fungal infections including vaginal candidiasis, oral and esophageal thrush, systemic candidiasis, fungal skin infections
₦6,000.00
Buy NowDonyflu Tablet 200mg is a synthetic triazole antifungal agent that provides comprehensive treatment for various fungal infections. Its broad-spectrum activity targets multiple types of fungal organisms.
Uses
Donyflu Tablet 200mg treats numerous fungal infections including vaginal candidiasis, oral and esophageal thrush, systemic candidiasis, cryptococcal meningitis, fungal skin infections, and prophylactic treatment for immunocompromised patients at risk of fungal infections.
Benefits
- Broad-spectrum antifungal action
- Effective against multiple fungal species
- Oral tablet provides convenient administration
- Penetrates multiple body tissues
- Treats systemic and localized fungal infections
- Single-dose treatment for many conditions
- Minimal side effect profile
- Suitable for various patient populations
How It Works
Donyflu Tablet 200mg works by inhibiting the fungal enzyme 14-α-demethylase, which is crucial for ergosterol production. This disrupts fungal cell membrane formation, preventing fungal growth and causing cell death.
Duration of Action
Peak plasma concentrations occur within 1-2 hours after oral administration. The medication remains active in the body for 24-72 hours, with a half-life of approximately 30 hours, allowing for extended antifungal protection.
Dosage
| Condition | Recommended Dosage | Frequency |
|---|---|---|
| Vaginal Candidiasis | 150mg | Single dose |
| Oral Thrush | 200mg | Once daily for 1-2 weeks |
| Systemic Candidiasis | 400mg | First dose, then 200mg daily |
| Cryptococcal Meningitis | 400mg | First dose, then 200-400mg daily |
| Prophylaxis | 50-200mg | Once daily |
Warnings
Exercise caution in patients with liver disease, kidney disorders, or compromised immune systems. Potential for serious drug interactions exists. Discontinue if signs of liver toxicity or severe skin reactions occur.
Side Effects
Common side effects include headache, nausea, abdominal pain, diarrhea, and skin rash. Rare but serious side effects may include liver dysfunction, severe allergic reactions, and potential cardiac complications.
Pregnancy and Breastfeeding
Use during pregnancy only when potential benefits outweigh risks. Limited data suggests caution. Consult healthcare provider before use during pregnancy or while breastfeeding.
Interactions
- Warfarin (increased anticoagulant effect)
- Oral hypoglycemics (altered blood sugar levels)
- Phenytoin (altered drug metabolism)
- Rifampicin (reduced Fluconazole effectiveness)
- Statins (increased risk of muscle damage)
- Benzodiazepines (increased sedative effects)
- Cyclosporine (increased drug levels)
Precautions
Take exactly as prescribed. Avoid alcohol during treatment. Complete full course of medication. Monitor liver function during prolonged use. Report any unusual symptoms to healthcare provider immediately.
Important Information
Donyflu Tablet 200mg is a powerful antifungal medication that should be used under medical supervision. Take with or without food. Store at room temperature away from moisture and heat. Keep out of reach of children.
Product Image Highlights
Tailored for Your Unique Needs
| Category | Dosage Instructions |
|---|---|
| Vaginal Candidiasis | 150 mg as a single dose. |
| Oropharyngeal Candidiasis | 200 mg on the first day, followed by 100 mg once daily for 7–14 days. |
| Esophageal Candidiasis | 200 mg on the first day, followed by 100 mg once daily for 14–30 days. |
| Systemic Candidiasis | 400 mg on the first day, followed by 200 mg once daily for at least 2 weeks after negative blood cultures. |
| Cryptococcal Meningitis | 400 mg on the first day, followed by 200 mg–400 mg once daily for 6–8 weeks (or longer if needed). |
| Maintenance for Cryptococcal Meningitis | 200 mg once daily. |
| Tinea Infections (Skin and Nails) | 150 mg once weekly for 2–4 weeks (up to 6 weeks for athlete's foot). |
| Children | 3–12 mg/kg once daily, depending on the condition (maximum dose: 400 mg/day). |
| Patients with Renal Impairment | Dosage adjustment based on creatinine clearance: - CrCl ≥ 50 ml/min – No adjustment - CrCl < 50 ml/min – Give 50% of the usual dose. |
How to Use
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Take orally with or without food.
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Complete the full course, even if symptoms improve.
-
If a dose is missed, take it as soon as possible unless it's almost time for the next dose.
Important Information
-
Common side effects: Nausea, headache, dizziness, and abdominal pain.
-
Avoid alcohol while using this medication.
-
Monitor liver function if using long-term.
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