Flagyl 400mg Tablets contain the antibiotic medication Metronidazole, which is effective in treating a variety of anaerobic bacterial and protozoal infections. This prescription medication is a key component in the management of various conditions, including bacterial vaginosis, trichomoniasis, and intra-abdominal infections.
Uses
Flagyl 400mg Tablets are primarily used to treat the following conditions:
- Bacterial vaginosis
- Trichomoniasis (a sexually transmitted infection)
- Intra-abdominal infections
- Pelvic inflammatory disease
- Intra-abdominal abscesses
- Gastroenteritis caused by Clostridium difficile
Benefits
- Effectively treats anaerobic bacterial and protozoal infections
- Helps restore normal vaginal flora in bacterial vaginosis
- Eradicates Trichomonas parasite in trichomoniasis
- Manages serious intra-abdominal infections
- Reduces risk of post-surgical complications
- Helps eliminate Clostridium difficile in gastroenteritis
- Prevents recurrence of certain infections
- Cost-effective antibiotic treatment option
How It Works
Metronidazole disrupts the DNA structure of anaerobic bacteria and protozoans, leading to their death. This mechanism makes Flagyl particularly effective against organisms that thrive in low-oxygen environments throughout the body.
Dosage
Condition | Dosage | Treatment Duration |
---|---|---|
Bacterial vaginosis | 400mg twice daily | 7 days |
Trichomoniasis | 2g single dose | 1 day |
Intra-abdominal infections | 500mg three times daily | 7-10 days |
Take Flagyl with food to minimize gastrointestinal side effects and improve absorption.
Duration of Action
Symptom improvement typically occurs within 2-3 days of starting Flagyl 400mg treatment. Complete the full antibiotic course as prescribed, usually 7-10 days, to ensure complete infection eradication and prevent resistance development.
Side Effects
Common side effects include nausea, metallic taste, headache, and gastrointestinal discomfort. Serious but rare side effects may include allergic reactions, central nervous system effects, and darkening of urine. Most side effects resolve after completing treatment.
Warning
Avoid alcohol consumption during treatment and for 3 days after completion, as it can cause a disulfiram-like reaction with severe nausea and vomiting. Discontinue Flagyl and seek medical attention if severe side effects occur. Not recommended for patients with certain neurological disorders.
Pregnancy and Breastfeeding
Flagyl 400mg Tablets are generally considered safe during pregnancy and breastfeeding when prescribed by a healthcare provider. However, discuss potential risks with your doctor, especially during the first trimester of pregnancy when organ development occurs.
Interaction
- May interact with anticoagulants, lithium, and certain antidepressants
- Can affect alcohol metabolism, leading to disulfiram-like reaction
- Possible interaction with certain cancer medications
- May interact with cholestyramine and colestipol
Precaution
Take with food to minimize stomach upset. Inform healthcare providers about liver disease, kidney problems, or neurological conditions before starting treatment. Monitor for signs of peripheral neuropathy during prolonged use. Avoid driving if experiencing dizziness or confusion.
Important Information
Complete the full course of Flagyl treatment as directed, even if symptoms improve early. Store at room temperature, away from moisture and heat. Report unusual side effects to your healthcare provider immediately. Sexual partners should be treated simultaneously for sexually transmitted infections to prevent reinfection.
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