Flagyl Syrup 4% is a liquid oral formulation containing the antibiotic Metronidazole. This metronidazole suspension is designed to effectively treat a variety of anaerobic bacterial and protozoal infections in children and adults who have difficulty swallowing tablets.
Uses
Flagyl Syrup 4% is primarily used for the treatment of the following conditions in pediatric and adult patients:
- Bacterial vaginosis
- Trichomoniasis (a sexually transmitted infection)
- Intra-abdominal infections
- Pelvic inflammatory disease
- Clostridium difficile-associated diarrhea
Benefits
- Provides an alternative liquid formulation for patients who cannot take tablets
- Effectively treats anaerobic bacterial and protozoal infections
- Helps restore normal vaginal flora in bacterial vaginosis
- Eradicates Trichomonas parasite in trichomoniasis
- Manages serious intra-abdominal infections
- Reduces risk of post-surgical complications
- Helps eliminate Clostridium difficile in gastroenteritis
- Prevents recurrence of certain infections
- Convenient dosing for children and adults
How It Works
Metronidazole, the active ingredient in Flagyl Syrup 4%, disrupts the DNA structure of anaerobic bacteria and protozoans, leading to their death. This mechanism of action makes it particularly effective against organisms that thrive in low-oxygen environments.
Duration of Action
Symptom improvement is typically seen within 2-3 days of starting Flagyl Syrup 4% treatment. However, it is important to complete the full course of antibiotics as prescribed, usually 7-10 days, to ensure complete eradication of the infection.
Dosage
Dosage may vary based on the specific condition and patient’s age/weight. The healthcare provider will determine the appropriate dosage, which is typically:
- Children: 7.5 mg/kg every 8 hours
- Adults: 15-30 ml (equivalent to 600-1200 mg of metronidazole) every 8 hours
Side Effects
Common side effects may include nausea, vomiting, metallic taste, headache, and gastrointestinal discomfort. Serious side effects are rare but may include allergic reactions, central nervous system effects, and darkening of urine.
Warning
Avoid alcohol consumption during and for 3 days after treatment, as it can cause a disulfiram-like reaction. Discontinue use and seek medical attention if severe side effects occur. Not recommended for patients with certain neurological disorders.
Pregnancy and Breastfeeding
Flagyl Syrup 4% is generally considered safe for use during pregnancy and breastfeeding when prescribed by a healthcare provider. However, the potential risks should be discussed with the doctor, especially during the first trimester of pregnancy.
Interactions
- May interact with anticoagulants, lithium, and certain antidepressants
- Can affect the metabolism of alcohol, leading to a disulfiram-like reaction
- Possible interaction with certain cancer medications
- May interact with cholestyramine and colestipol
Important Information
Take Flagyl Syrup 4% with food to minimize gastrointestinal side effects. Complete the full course of treatment as directed, even if symptoms improve. Store the medication at room temperature, away from moisture and heat. Shake well before each use. Report any unusual side effects to your healthcare provider.
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