Methimez 10mg Tablet (Methimazole) x90

Methimez 10mg Tablet contains Methimazole, an antithyroid medication used to treat hyperthyroidism. This medication reduces thyroid hormone production by blocking thyroid peroxidase enzyme, helping restore normal thyroid function levels.

Uses

Methimez 10mg Tablet treats hyperthyroidism (overactive thyroid) including Graves’ disease, toxic multinodular goiter, and thyrotoxicosis. It’s used as primary treatment or to prepare patients for radioiodine therapy or thyroid surgery. The medication helps control symptoms like rapid heartbeat, weight loss, and anxiety.

Benefits

• Effectively reduces thyroid hormone production
• Controls hyperthyroid symptoms like palpitations and tremors
• Helps normalize heart rate and blood pressure
• Reduces anxiety and nervousness associated with hyperthyroidism
• Prevents thyroid storm in severe cases
• Allows weight stabilization and improved sleep
• Prepares patients for definitive thyroid treatments
• Restores normal metabolic function
• Improves quality of life in hyperthyroid patients

How It Works

Methimazole inhibits thyroid peroxidase, an enzyme essential for thyroid hormone synthesis. By blocking this enzyme, it prevents the incorporation of iodine into thyroglobulin, reducing production of T3 and T4 hormones. This action gradually normalizes thyroid function and alleviates hyperthyroid symptoms.

Dosage

Take Methimez at the same time daily, preferably with food to reduce stomach irritation. Dosage adjustments based on thyroid function tests.

Duration of Action

Methimez begins working within days but noticeable symptom improvement takes 2-4 weeks. Peak therapeutic effects occur after 4-6 weeks of regular treatment. The medication has a half-life of 6-8 hours, requiring daily dosing for sustained thyroid suppression.

Side Effects

Common side effects include skin rash, itching, joint pain, and mild gastrointestinal upset. Less common but serious effects include agranulocytosis (low white blood cell count), liver toxicity, and vasculitis. Most side effects are dose-related and reversible upon discontinuation.

Warning

Methimez can cause serious blood disorders including agranulocytosis, which may be fatal. Regular blood monitoring is essential. Discontinue immediately if signs of infection, sore throat, fever, or unusual bleeding occur. Liver function should be monitored as severe hepatotoxicity can occur.

Pregnancy and Breastfeeding

Methimez crosses the placenta and can cause fetal goiter and hypothyroidism. Use only if benefits outweigh risks, with close monitoring. Propylthiouracil is preferred during pregnancy. Methimez passes into breast milk; monitor infant thyroid function if breastfeeding while taking this medication.

Interaction

• May increase effects of anticoagulants like warfarin
• Beta-blockers may mask hyperthyroid symptoms during treatment
• Possible interaction with theophylline requiring dosage adjustment
• May affect insulin or oral diabetes medication requirements
• Potential interaction with digitalis medications
• Iodine-containing substances may reduce effectiveness

Precaution

Regular blood tests are required to monitor white blood cell count and liver function. Patients should immediately report signs of infection, unusual bleeding, or jaundice. Use with caution in patients with liver disease. Avoid excessive iodine intake from foods or supplements during treatment.

Important Information

Methimez requires regular medical supervision with periodic blood tests and thyroid function monitoring. Treatment duration typically ranges from 12-18 months. Do not stop taking medication without consulting your doctor as symptoms may return. Store at room temperature away from moisture and heat. Inform all healthcare providers about Methimez use before any medical procedures.