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Propycil 50mg Tablets (Propylthiouracil) x50

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Propycil 50mg Tablets are used for the treatment of hyperthyroidism (overactive thyroid), graves’ disease and toxic multinodular goiter

25,000.00

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Availability: In Stock
SKU:PRI7632

Propycil 50mg Tablets contain the active ingredient Propylthiouracil, an antithyroid medication used to treat hyperthyroidism (overactive thyroid). Propylthiouracil works by reducing the production of thyroid hormones, helping to manage symptoms and restore normal thyroid function. Propycil 50mg Tablets provide an effective and convenient treatment option for patients with hyperthyroidism.

Uses

Propycil 50mg Tablets are used for the treatment of:

  • Hyperthyroidism (overactive thyroid)
  • Graves’ disease
  • Toxic multinodular goiter
  • Thyroid storm (a severe form of hyperthyroidism)

Benefits

  • Reduces the production of thyroid hormones, helping to alleviate symptoms of hyperthyroidism
  • Provides effective management of Graves’ disease, toxic multinodular goiter, and other causes of hyperthyroidism
  • Offers a convenient oral tablet formulation for easy administration
  • Can be used as a long-term treatment option or as a pre-treatment before thyroid surgery or radioactive iodine therapy

Dosage

The dosage of Propycil 50mg Tablets will be determined by your healthcare provider based on your individual condition, age, weight, and response to treatment. The usual starting dose for adults is 300-450 mg daily, divided into three doses every 8 hours. Your doctor may adjust your dosage as needed to achieve optimal control of your thyroid function.

Mechanism of Action

Propylthiouracil, the active ingredient in Propycil 50mg Tablets, works by inhibiting the synthesis of thyroid hormones in the thyroid gland. It does this by blocking the enzyme thyroperoxidase, which is essential for the production of thyroid hormones. By reducing the production of these hormones, Propylthiouracil helps to manage the symptoms of hyperthyroidism and restore normal thyroid function.

Side Effects

Most people tolerate Propycil 50mg Tablets well, but some may experience side effects such as:

  • Skin rash or itching
  • Joint pain
  • Gastrointestinal issues (nausea, vomiting, loss of appetite)
  • Altered taste sensation
  • Headache or dizziness

Rarely, more serious side effects may occur, such as liver problems, low white blood cell count, or lupus-like syndrome. Seek immediate medical attention if you experience symptoms such as yellowing of the skin or eyes, persistent fever, or severe abdominal pain.

Warning

Propycil 50mg Tablets may cause liver damage in rare cases. Regular blood tests to monitor liver function are recommended during treatment. Inform your healthcare provider if you have a history of liver disease before starting treatment with Propycil 50mg Tablets. Pregnant women should use Propycil 50mg Tablets with caution, as it may cross the placenta and affect the fetal thyroid gland.

Important Information

Take Propycil 50mg Tablets exactly as prescribed by your healthcare provider. Do not change your dose or stop taking the medication without consulting your doctor. If you miss a dose, take it as soon as you remember, but skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose. Store Propycil 50mg Tablets at room temperature, away from moisture and heat.

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Category Dosage Instructions
Adults (Initial Dosage) - 100 mg to 300 mg daily, divided into three equal doses (e.g., one 50 mg tablet taken three times a day). - Severe cases: up to 600 mg per day in divided doses.
Adults (Maintenance Dosage) - 50 mg to 150 mg per day, taken in divided doses, once thyroid levels are controlled.
Children (Initial Dosage) - 5 mg to 7 mg per kg of body weight per day, in divided doses.
Children (Maintenance Dosage) - Adjusted based on response and thyroid function tests, typically lower than the initial dosage.
Administration - Take with a full glass of water. - Usually taken three times a day. - Maintain consistent timing for even levels in the bloodstream.
Monitoring - Regular thyroid function tests are required. - Periodic liver function tests may also be necessary due to possible effects on liver function.
Precautions - Inform your doctor of any history of liver disease or blood disorders. - Report unusual symptoms such as sore throat, fever, or jaundice immediately.
Note: Always follow your doctor’s guidance regarding dosage adjustments and medical supervision. Avoid sudden discontinuation of the medication.

Monitoring:

  • Regular blood tests are necessary to monitor thyroid function and adjust the dosage accordingly.
  • Periodic liver function tests may also be required since propylthiouracil can affect liver function.

Precautions:

  • Inform your doctor if you have a history of liver disease, blood disorders, or any other medical conditions.
  • Report any unusual symptoms such as sore throat, fever, yellowing of the skin or eyes, unusual bleeding or bruising, or signs of infection to your doctor immediately, as these may indicate serious side effects.
  • Avoid abrupt discontinuation of the medication without consulting your healthcare provider, as this can lead to a rapid return of hyperthyroid symptoms.

Pregnancy and Breastfeeding:

  • Propylthiouracil is often preferred during the first trimester of pregnancy due to its lower risk of teratogenic effects compared to other antithyroid medications.
  • Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Missed Dose:

  • If you miss a dose, take it as soon as you remember.
  • If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule.
  • Do not double the dose to catch up.
Always follow your healthcare provider’s specific instructions regarding the dosage and administration of Propycil (Propylthiouracil) and have regular check-ups to ensure the medication is working effectively and safely.

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