Norbactin 400mg Tablet contains norfloxacin, a broad-spectrum fluoroquinolone antibiotic. This oral medication offers potent antimicrobial activity against various gram-negative and some gram-positive bacteria. Designed for convenient administration, Norbactin provides effective treatment for urinary tract and gastrointestinal infections.
Uses
Norbactin 400mg Tablet is primarily used to treat:
- Uncomplicated urinary tract infections
- Complicated urinary tract infections
- Acute bacterial prostatitis
- Gastroenteritis is caused by susceptible organisms
- Traveler’s diarrhea
Benefits
- Broad-spectrum activity against many urinary tract pathogens
- Effective against some fluoroquinolone-resistant strains
- Convenient twice-daily dosing
- Good oral bioavailability
- Reaches high concentrations in urinary tract tissues
- Suitable for both treatment and prophylaxis of UTIs
- Effective in treating some gastrointestinal infections
How It Works
Norfloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This action leads to rapid bacterial cell death, making it bactericidal.
Dosage
The typical adult dose is 400mg twice daily for 3-10 days, depending on the type and severity of infection. For uncomplicated UTIs, a 3-day course may be sufficient. Always follow your doctor’s specific dosing instructions.
Side Effects
Common side effects may include nausea, headache, dizziness, and mild digestive disturbances. Rarely, more serious side effects such as tendon inflammation or rupture, peripheral neuropathy, or severe allergic reactions may occur. Consult your healthcare provider if you experience any unusual symptoms.
Warning
Norbactin 400mg Tablet should only be used under medical supervision. It should be avoided in patients with a history of tendon disorders related to quinolone use. Discontinue use and seek immediate medical attention if signs of tendinitis, tendon rupture, or severe allergic reactions occur.
Pregnancy and Breastfeeding
Norbactin 400mg Tablet is not recommended during pregnancy due to potential risks to fetal development. It is excreted in human milk, so it’s not recommended for nursing mothers. Consult your healthcare provider for alternative treatments if you are pregnant or breastfeeding.
Interaction
- May increase the effect of oral anticoagulants
- Antacids, iron, and zinc supplements can reduce absorption
- Can increase the risk of tendon problems when used with corticosteroids
- May enhance the effects of caffeine
- Potential interaction with cyclosporine and theophylline
Important Information
Complete the full course of treatment as prescribed, even if symptoms improve. Take the tablets with a full glass of water, at least 1 hour before or 2 hours after meals. Avoid dairy products, calcium-fortified juices, and antacids within 2 hours of taking Norbactin. Stay well-hydrated during treatment. Avoid excessive sun exposure as it may increase the risk of photosensitivity reactions. If you experience any signs of tendon pain or inflammation, stop taking the medication and contact your healthcare provider immediately.
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