Pradaxa 110mg is an anticoagulant medication containing the active ingredient dabigatran etexilate, formulated as capsules. It inhibits thrombin to prevent dangerous blood clots, offering a vital treatment option for patients at risk of thrombotic events.
Uses
Pradaxa 110mg is prescribed to:
- Reduce stroke risk in patients with non-valvular atrial fibrillation
- Treat and prevent recurrence of dangerous blood clots such as deep vein thrombosis (DVT) or pulmonary embolism (PE)
Benefits
- Reduces the chance of debilitating or fatal strokes in atrial fibrillation patients
- Prevents painful and life-threatening deep vein clots
- Offers an alternative to traditional anticoagulants
- Does not require routine coagulation monitoring
How It Works
Dabigatran, the active ingredient in Pradaxa 110mg, functions as a direct thrombin inhibitor. By binding to and inhibiting thrombin, a crucial enzyme in the blood coagulation process, it effectively reduces the formation of abnormal and dangerous blood clots.
Dosage
The typical Pradaxa 110mg dosage for non-valvular atrial fibrillation patients is one 110mg capsule taken twice daily. For clot prevention/treatment, it is initially given twice daily after parenteral anticoagulation. The duration of treatment depends on individual risk profiles and should be determined by a healthcare professional.
Duration of Action
Pradaxa 110mg reaches peak plasma concentrations within 1-3 hours after oral administration. Its anticoagulant effect lasts for approximately 24 hours, necessitating twice-daily dosing to maintain consistent blood levels.
Side Effects
Common side effects may include gastrointestinal discomfort and bleeding gums. More serious side effects can include:
- Major bleeding events
- Allergic reactions
- Gastrointestinal ulcers
If you experience any unusual symptoms, contact your healthcare provider immediately.
Warning
- Increased bleeding risk – patients should be monitored for signs of bleeding
- Kidney dysfunction requires dose adjustments – regular renal function monitoring is essential
- Capsules should not be opened or sprinkled – must be swallowed whole
Pregnancy and Breastfeeding
The safety of Pradaxa 110mg during pregnancy and breastfeeding has not been fully established. Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
Interactions
- May interact with other anticoagulants or antiplatelet drugs, increasing bleeding risk
- Certain medications can affect the metabolism of Pradaxa
- Always inform your healthcare provider about all medications you’re taking
Important Information
Pradaxa 110mg requires regular monitoring of renal function. Other drugs can interact with Pradaxa, so always consult your physician about potential interactions. Stopping Pradaxa should always be done under medical guidance to prevent increased risk of thrombotic events. Store capsules in the original package to protect from moisture. If you miss a dose, take it as soon as you remember, unless it’s close to your next scheduled dose.
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