SPC Liquid Quinine Syrup 150mg/5ml x100ml

SPC Liquid Quinine Syrup 150mg is an antimalarial medication containing 150mg of quinine per 5ml dose. This liquid formulation provides effective treatment for malaria, particularly severe cases, and is especially suitable for patients who cannot take oral tablets.

Uses

SPC Liquid Quinine Syrup treats malaria caused by Plasmodium species, including severe and complicated malaria cases. It’s particularly effective against chloroquine-resistant strains and is used when other antimalarials are ineffective or contraindicated. The syrup is ideal for children and adults with swallowing difficulties.

Benefits

• Effective against severe and complicated malaria
• Works on chloroquine-resistant Plasmodium strains
• Rapid reduction of parasitemia and fever
• Suitable for patients unable to take tablets
• Easy administration in pediatric patients
• Proven efficacy in life-threatening malaria cases
• Can be used in combination therapy
• Liquid form allows accurate dosing
• Reduces risk of severe malaria complications

How It Works

Quinine interferes with the malaria parasite’s ability to break down and digest hemoglobin in red blood cells. It disrupts the parasite’s metabolic processes and prevents its replication within blood cells. This action leads to parasite death and clearance from the bloodstream, reducing fever and other malaria symptoms.

Dosage

Take SPC Liquid Quinine Syrup with or after meals to reduce stomach irritation. Measure dose accurately using provided measuring device.

Duration of Action

SPC Liquid Quinine Syrup begins working within 2-4 hours of administration. Fever typically starts reducing within 24-48 hours. The medication reaches peak blood levels within 1-3 hours and has a half-life of 8-14 hours, requiring dosing every 8 hours for sustained effect.

Side Effects

Common side effects include nausea, vomiting, diarrhea, and stomach pain. Patients may experience headache, dizziness, or ringing in ears (tinnitus). Visual disturbances, temporary hearing loss, or skin rash may occur. Severe reactions include cardiac arrhythmias or severe allergic reactions requiring immediate medical attention.

Warning

Use only under medical supervision for confirmed malaria diagnosis. Quinine can cause serious cardiac arrhythmias and should be avoided in patients with heart rhythm disorders. Monitor blood glucose levels as hypoglycemia may occur. Discontinue if severe allergic reactions, irregular heartbeat, or significant hearing/vision changes develop.

Pregnancy and Breastfeeding

SPC Liquid Quinine Syrup can be used during pregnancy when benefits outweigh risks, particularly for severe malaria which poses greater maternal and fetal risks. Quinine passes into breast milk but breastfeeding can usually continue under medical supervision in malaria-endemic areas.

Interaction

• May increase risk of cardiac effects with certain heart medications
• Possible interaction with anticoagulants, increasing bleeding risk
• May affect blood sugar levels when used with diabetes medications
• Potential interaction with certain antibiotics and antifungals
• Could alter effectiveness of some seizure medications
• May interact with muscle relaxants, increasing their effects

Precaution

Use with extreme caution in patients with cardiac disorders, glucose-6-phosphate dehydrogenase deficiency, or myasthenia gravis. Monitor patients with kidney or liver impairment closely. Avoid in those with known quinine hypersensitivity. Regular monitoring of blood glucose, cardiac function, and hearing may be necessary during treatment.

Important Information

SPC Liquid Quinine Syrup is a prescription medication requiring medical supervision throughout treatment. Complete the full prescribed course even if symptoms improve. Store at room temperature, protected from light. Shake well before each use. Do not exceed recommended dosage. If vomiting occurs within 30 minutes of taking dose, consult healthcare provider about repeating the dose.