Thiapril Tablets (Hydrochlorothiazide) x30

Thiapril Tablets combine Ramipril (ACE inhibitor) and Hydrochlorothiazide (thiazide diuretic) to effectively manage hypertension. This dual-action medication is designed for patients requiring multiple drugs to control blood pressure. Each pack contains 30 tablets.

Uses

Thiapril Tablets treat high blood pressure (hypertension) in patients not adequately controlled on single medication therapy. They help manage cardiovascular risks associated with hypertension and provide enhanced blood pressure control through dual mechanisms.

Benefits

• Provides dual mechanism for superior blood pressure control
• More effective than either component used alone
• Convenient once-daily dosing improves patient compliance
• Reduces need for multiple separate medications
• Helps prevent hypertension-related complications
• Cost-effective treatment option for blood pressure management

How It Works

Ramipril inhibits angiotensin-converting enzyme (ACE), causing blood vessel relaxation and reduced blood pressure. Hydrochlorothiazide acts as a diuretic, increasing water and salt excretion through urine. Together, they provide complementary blood pressure reduction through different pathways.

Dosage

Take orally with water. Dosage strength should be determined by healthcare provider based on individual response and needs.

Duration of Action

Thiapril begins working within 1-2 hours of administration. Peak effects occur at 3-6 hours for the diuretic component and 2-4 hours for the ACE inhibitor. The medication provides 24-hour blood pressure control, making once-daily dosing effective.

Side Effects

Common side effects include dizziness, headache, fatigue, dry cough (from ramipril), and increased urination (from hydrochlorothiazide). Serious but rare side effects include allergic reactions, severe electrolyte imbalances, or liver problems. Seek immediate medical attention for severe dizziness, fainting, or jaundice.

Warning

Do not use Thiapril if you have history of angioedema with ACE inhibitors or during pregnancy due to fetal harm risk. Patients with kidney problems or electrolyte imbalances require close monitoring. Do not stop abruptly as this may cause sudden blood pressure increases.

Pregnancy and Breastfeeding

Thiapril is contraindicated during pregnancy due to risk of serious fetal harm. Women should use effective contraception during treatment. Consult healthcare provider regarding use while breastfeeding as both components may pass into breast milk.

Interaction

• May interact with other blood pressure medications causing excessive hypotension
• NSAIDs and potassium supplements can affect effectiveness
• May interact with certain diabetes medications altering blood sugar
• Alcohol should be used cautiously as it may enhance hypotensive effects
• Salt substitutes containing potassium require careful monitoring

Precaution

Take consistently at the same time daily for optimal effectiveness. Regular blood pressure monitoring and periodic blood tests are necessary. Stay adequately hydrated but avoid excessive fluid intake. Inform all healthcare providers about Thiapril use before procedures or starting new medications.

Important Information

Thiapril requires regular monitoring of blood pressure, kidney function, and electrolyte levels. Report persistent cough, swelling, or unusual fatigue to your doctor. Store at room temperature away from moisture and heat. This medication is most effective when combined with lifestyle modifications including diet, exercise, and stress management.