Vesizen 10mg Tablet (Solifenacin) x30

Vesizen 10mg Tablet contains Solifenacin Succinate, an antimuscarinic agent that targets the bladder. This medication reduces overactive bladder symptoms including urinary frequency, urgency, and incontinence by relaxing bladder muscles.

Uses

Vesizen 10mg Tablet treats overactive bladder syndrome characterized by urinary urgency, frequency, and incontinence. It helps manage symptoms in patients with detrusor muscle overactivity, reducing sudden urges to urinate and decreasing unwanted urine leakage.

Benefits

• Reduces urinary frequency during day and night
• Decreases sudden urges to urinate
• Minimizes episodes of urge incontinence
• Increases bladder capacity
• Improves control over bladder function
• Reduces nocturia (nighttime urination)
• Improves quality of sleep
• Enhances social confidence and activity
• Improves overall quality of life

How It Works

Solifenacin Succinate in Vesizen selectively blocks muscarinic receptors in the bladder detrusor muscle. This action inhibits involuntary bladder contractions, relaxes the detrusor muscle, and increases bladder capacity. The medication specifically targets the bladder with fewer effects on other organs.

Dosage

Take Vesizen with water, with or without food. Swallow tablet whole; do not crush or chew. Take at the same time each day to maintain consistent blood levels.

Duration of Action

Vesizen begins working within 3-8 hours after administration. Full therapeutic effects typically develop after 2-4 weeks of consistent use. The drug’s effects last approximately 24 hours, allowing for once-daily dosing. Maximum benefits may take up to 12 weeks of regular treatment.

Side Effects

Common side effects include dry mouth, constipation, and blurred vision. Less frequent effects include dry eyes, headache, and digestive discomfort. Rare but serious side effects include severe constipation, urinary retention, allergic reactions, and confusion. Most side effects are mild to moderate and diminish with continued use.

Warning

Do not use Vesizen if you have urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, or severe liver disease. Use with caution in patients with bladder outflow obstruction or gastrointestinal disorders. Seek immediate medical attention for severe allergic reactions, acute eye pain, or inability to urinate.

Pregnancy and Breastfeeding

Vesizen is not recommended during pregnancy unless clearly necessary. Limited data exists on safety during pregnancy. The medication passes into breast milk and may affect nursing infants. Breastfeeding women should either discontinue breastfeeding or avoid this medication based on healthcare provider guidance.

Interaction

• May enhance anticholinergic effects of other medications
• Potential decreased effectiveness when used with CYP3A4 inducers
• Increased drug concentration with CYP3A4 inhibitors like ketoconazole
• May interact with certain antipsychotics and antidepressants
• Possible interaction with metformin and other oral diabetes medications

Precaution

Use cautiously in patients with renal or hepatic impairment, as dose adjustment may be needed. Monitor for signs of urinary retention in patients with bladder outflow obstruction. Exercise caution in hot environments as decreased sweating may increase risk of heat stroke. Avoid driving or operating machinery if experiencing blurred vision or drowsiness.

Important Information

Vesizen provides symptomatic relief but does not cure overactive bladder syndrome. Full benefits may require several weeks of treatment. Maintain adequate hydration while taking this medication, but avoid excessive fluid intake. Regular follow-up with healthcare provider is recommended to assess effectiveness and manage any side effects. Store at room temperature away from moisture and heat.