Zolat 400mg Tablet contains Albendazole, a broad-spectrum anthelmintic medication effective against various intestinal parasites. This potent anti-parasitic agent disrupts worm metabolism, eliminating common helminth infections and preventing complications from parasitic infestations.
Uses
Zolat 400mg Tablet treats intestinal worm infections including roundworms, hookworms, pinworms, whipworms, and tapeworms. It’s also effective against hydatid disease, neurocysticercosis, and certain tissue-dwelling parasitic infections. Zolat may be prescribed as individual treatment or as part of community deworming programs.
Benefits
- Eliminates multiple types of intestinal parasites with single dose
- Treats both intestinal and tissue parasitic infections
- Highly effective against resistant strains of worms
- Prevents complications of untreated parasitic infections
- Simple dosing regimen with high compliance rate
- Can be used in mass deworming programs
- Improves nutritional status by eliminating parasites
- Reduces transmission of parasitic infections in communities
- Effective in both adults and children (dose adjusted)
How It Works
Albendazole in Zolat 400mg Tablet selectively inhibits tubulin polymerization in parasites, disrupting their cellular structure and energy metabolism. This prevents glucose uptake in worms, depleting their glycogen stores and blocking ATP production. The parasites become immobilized and eventually die, then are expelled from the body naturally.
Dosage
Infection Type | Adult Dosage | Duration |
---|---|---|
Common intestinal worms | 400mg (1 tablet) | Single dose |
Strongyloidiasis | 400mg (1 tablet) daily | 3 days |
Neurocysticercosis | 400mg (1 tablet) twice daily | 8-30 days |
Take Zolat with meals, preferably fatty foods, to increase absorption. Crushing tablet for children should be done only under medical supervision.
Duration of Action
Zolat begins working within hours of administration. For intestinal parasites, the medication remains effective for 24-48 hours. Full clearance of parasites typically occurs within 3 days for common intestinal worms. For tissue infections like neurocysticercosis, treatment duration is longer with continued action throughout the prescribed period.
Side Effects
Most patients tolerate Zolat well. Common side effects include mild abdominal pain, nausea, vomiting, or dizziness. Headache and temporary hair loss occur rarely. In cases of heavy parasite load, dying parasites may cause temporary digestive discomfort or mild fever as they are expelled from the body.
Warning
Do not use Zolat during the first trimester of pregnancy. Severe allergic reactions are rare but require immediate medical attention. For patients with neurocysticercosis, monitor for increased intracranial pressure as parasites die. May occasionally cause elevation of liver enzymes; discontinue if signs of liver dysfunction appear.
Pregnancy and Breastfeeding
Zolat is contraindicated during the first trimester of pregnancy due to potential teratogenic effects. It may be used in second and third trimesters if benefits clearly outweigh risks. Limited amounts pass into breast milk; consider temporarily suspending breastfeeding for 24 hours after a single dose when treating nursing mothers.
Interaction
- May increase levels of certain anti-seizure medications
- Effectiveness reduced when taken with high-dose vitamin C
- Dexamethasone may increase albendazole levels in blood
- Cimetidine may increase risk of liver toxicity
- May interact with certain HIV medications
Precaution
Use cautiously in patients with liver disease or cirrhosis, as Zolat is metabolized in the liver. Monitor liver function if prolonged treatment is required. Individuals with cystic or hydatid disease should take under close medical supervision. Complete the full prescribed course even after symptoms improve to prevent recurrence.
Important Information
Zolat 400mg Tablet treats parasite infection but does not prevent reinfection. Maintain good hygiene practices including handwashing, proper food preparation, and clean drinking water. Family members or close contacts may need simultaneous treatment for some infections. Follow-up stool examination may be recommended 2-3 weeks after treatment to confirm parasite clearance.
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