Shal’Artem Forte Tablets (Artemether) x6

Shal’Artem Forte Tablets are a potent antimalarial medication combining Artemether (80mg) and Lumefantrine (480mg). This artemisinin-based combination therapy (ACT) is designed to effectively treat acute, uncomplicated malaria caused by Plasmodium falciparum, including in areas with multi-drug resistant strains.

Uses

Shal’Artem Forte is primarily used for:

• Treatment of acute, uncomplicated malaria caused by P. falciparum
• Management of malaria in areas with known drug resistance
• First-line treatment in many malaria-endemic regions

Benefits

• Highly effective against P. falciparum malaria
• Combats drug-resistant strains of malaria parasites
• Rapid action in reducing parasite load
• Reduces risk of treatment failure
• Helps prevent progression to severe malaria
• Combination therapy reduces risk of drug resistance development
• Well-tolerated by most patients

How It Works

Artemether rapidly reduces the parasite biomass, while Lumefantrine eliminates residual parasites. Artemether interferes with the parasite’s ability to detoxify heme, leading to parasite death. Lumefantrine is believed to interfere with the conversion of heme to hemozoin, disrupting parasite growth and reproduction.

Dosage

The typical adult dosage is 1 tablet taken twice daily for 3 days (total of 6 tablets). Tablets should be taken with food or milk, preferably at the same times each day. Dosage may vary based on patient weight and age. Always follow your healthcare provider’s instructions.

Side Effects

Common side effects may include headache, dizziness, fatigue, loss of appetite, nausea, and abdominal pain. Most side effects are mild and transient. Serious side effects are rare but may include allergic reactions or cardiac issues.

Warning

Shal’Artem Forte should not be used in patients with severe malaria or in the first trimester of pregnancy unless no other suitable treatment is available. Patients with a history of cardiac problems should be monitored closely. Do not use for malaria prevention.

Interaction

Shal’Artem Forte may interact with various medications. Key interactions include:

• CYP3A4 inhibitors or inducers (e.g., ketoconazole, rifampicin)
• Antiretroviral medications
• Some antipsychotics (e.g., pimozide)
• Certain antibiotics (e.g., macrolides)
• QT-prolonging drugs
• Grapefruit juice

Always inform your healthcare provider about all medications you’re taking.

Important Information

Complete the full course of treatment even if symptoms improve. If vomiting occurs within 1 hour of taking a dose, repeat the dose. Follow-up with your healthcare provider to ensure complete parasite clearance. If symptoms persist or worsen, seek medical attention immediately. This medication does not prevent malaria transmission to others. Continue to use protective measures against mosquito bites.