Actrapid is a fast-acting soluble human insulin that contains 100 IU/mL of regular insulin. This clear, water-soluble solution provides rapid blood glucose control. Manufactured through recombinant DNA technology, Actrapid delivers precise insulin therapy for diabetes management.
Uses
Actrapid is indicated for the treatment of diabetes mellitus in patients requiring insulin therapy. It’s particularly effective for controlling mealtime blood glucose spikes, managing diabetic ketoacidosis, and providing insulin coverage during surgery or acute illness.
Benefits
- Provides rapid blood glucose control
- Offers precise dose adjustments
- Compatible with insulin pumps
- Suitable for intravenous administration
- Effective for emergency glucose management
- Can be mixed with intermediate-acting insulin
- Allows flexible meal timing
- Demonstrates consistent absorption pattern
How It Works
Actrapid functions by binding to insulin receptors, facilitating glucose uptake into cells and inhibiting hepatic glucose production. Its rapid action profile closely mimics the body’s natural mealtime insulin response, providing effective post-prandial glucose control.
Dosage
Usage Type | Administration Time | Recommended Use |
---|---|---|
Mealtime | 15-30 mins before meals | Based on carb intake |
Pump Therapy | As programmed | According to pump settings |
Hospital Use | As needed | Per protocol |
Duration of Action
Onset begins within 15-30 minutes of injection, with peak effect occurring between 1-3 hours. The duration of action typically lasts 4-6 hours. Individual response may vary based on dosage and patient factors.
Side Effects
Common side effects include injection site reactions, hypoglycemia, and lipodystrophy. Serious side effects may include severe hypoglycemia or allergic reactions. Regular blood glucose monitoring is essential to minimize risks.
Warning
Risk of severe hypoglycemia if dosing is incorrect or meals are delayed. Never share insulin pens or syringes. Monitor blood sugar closely during dose adjustments. Seek immediate medical attention for severe hypoglycemia or allergic reactions.
Pregnancy and Breastfeeding
Actrapid is safe for use during pregnancy and breastfeeding under medical supervision. Insulin requirements typically change during pregnancy, necessitating frequent monitoring and dose adjustments.
Interactions
- Beta-blockers may mask hypoglycemia symptoms
- Oral diabetes medications may enhance effects
- Corticosteroids increase insulin requirements
- MAO inhibitors may increase hypoglycemic effect
- Alcohol may intensify blood sugar lowering
Precautions
Regular blood glucose monitoring is crucial. Rotate injection sites to prevent tissue changes. Always carry a quick-acting sugar source. Adjust doses for changes in diet, exercise, or illness. Store properly according to manufacturer guidelines.
Important Information
Inspect Actrapid before each use – it should be clear and colorless. Never freeze or expose to temperature extremes. Carry medical identification indicating diabetes and insulin use. Schedule regular medical check-ups for dose adjustments and treatment monitoring. For optimal results with Actrapid, maintain consistent daily routines and meal timing patterns.
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