Atacand 16mg Tablet contains Candesartan Cilexetil, an angiotensin receptor blocker (ARB) used to treat high blood pressure and heart failure. This medication helps relax blood vessels, reducing blood pressure and improving heart function.
Uses
Atacand 16mg treats hypertension (high blood pressure) in adults and children over 6 years. It’s also prescribed for heart failure to improve symptoms and reduce hospitalizations. Atacand can be used alone or combined with other blood pressure medications for optimal control.
Benefits
- Effectively lowers blood pressure
- Reduces risk of stroke and heart attack
- Improves heart failure symptoms
- Protects kidney function in diabetic patients
- Well-tolerated with fewer side effects than ACE inhibitors
- Does not cause persistent dry cough
- Provides 24-hour blood pressure control
- Reduces cardiovascular mortality risk
- Can be combined safely with other antihypertensives
How It Works
Candesartan blocks angiotensin II receptors, preventing blood vessel constriction and aldosterone release. This action relaxes blood vessels, reduces blood volume, and lowers blood pressure. In heart failure, Atacand reduces heart workload and improves pumping efficiency by decreasing peripheral resistance.
Dosage
Indication | Starting Dose | Maximum Daily Dose |
---|---|---|
Hypertension | 8-16mg once daily | 32mg once daily |
Heart Failure | 4mg once daily | 32mg once daily |
Take Atacand at the same time daily, with or without food. Dosage adjustments should be made gradually under medical supervision.
Duration of Action
Atacand begins lowering blood pressure within 2 hours of administration, with peak effects occurring at 3-6 hours. Full antihypertensive effects develop within 4-6 weeks of regular use. The medication provides 24-hour blood pressure control with once-daily dosing.
Side Effects
Common side effects include dizziness, headache, fatigue, and back pain. Some patients may experience upper respiratory tract infections or flu-like symptoms. Rare but serious effects include severe hypotension, kidney problems, or elevated potassium levels requiring medical attention.
Warning
Do not use Atacand 16mg during pregnancy as it can cause fetal harm or death. Monitor blood pressure regularly to avoid excessive hypotension. Use caution in patients with kidney disease, as the medication may worsen kidney function. Regular monitoring of kidney function and electrolytes is recommended.
Pregnancy and Breastfeeding
Atacand 16mg is contraindicated during pregnancy due to risk of fetal kidney damage, growth restriction, and death. Women of childbearing age should use effective contraception. Limited data exists on breastfeeding safety; consult healthcare provider to weigh benefits versus risks.
Interaction
- May increase lithium levels leading to toxicity
- Enhanced hypotensive effects with other blood pressure medications
- NSAIDs may reduce antihypertensive effectiveness
- Potassium supplements may increase hyperkalemia risk
- Diuretics may cause excessive blood pressure reduction initially
Precaution
Use cautiously in patients with severe heart failure, kidney artery stenosis, or volume depletion. Monitor kidney function and potassium levels regularly. Elderly patients may be more sensitive to blood pressure-lowering effects. Avoid sudden discontinuation in heart failure patients.
Important Information
Atacand 16mg requires regular medical monitoring for effectiveness and safety. Continue taking even when feeling well, as high blood pressure often has no symptoms. Store at room temperature away from moisture and heat. Maintain consistent dosing schedule and don’t miss doses. Lifestyle modifications including diet and exercise enhance medication effectiveness.
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