Cartinex 500mg Tablet contain ranolazine, an innovative anti-anginal medication specifically designed to treat chronic angina. This prescription medication works uniquely by regulating ion channels in heart muscle cells to improve cardiac function and reduce chest pain.
Uses
Cartinex 500mg serves as a targeted treatment for chronic angina when other treatments prove insufficient. It effectively manages chest pain, breathlessness, and fatigue associated with chronic angina, particularly beneficial for patients with limited treatment options.
Benefits
- Reduces frequency of angina episodes
- Decreases severity of chest pain attacks
- Improves exercise tolerance and daily activities
- Does not significantly affect heart rate or blood pressure
- Can be used with other cardiac medications
- Reduces need for sublingual nitroglycerin
- Improves quality of life in angina patients
- Provides sustained anti-anginal effects
- Well-tolerated as combination therapy
How It Works
Cartinex works by inhibiting the late sodium current in cardiac cells, which reduces calcium overload and improves diastolic relaxation. This mechanism decreases myocardial oxygen demand and improves coronary blood flow, reducing angina symptoms without affecting hemodynamic parameters like heart rate or blood pressure.
Dosage
Patient Group | Initial Dosage | Maximum Dosage |
---|---|---|
Adults | 500mg twice daily | 1000mg twice daily |
Elderly | 500mg twice daily | 750mg twice daily |
Take Cartinex with or without food. Swallow tablets whole; do not crush, chew, or split. Dosage may be adjusted based on response and tolerance.
Duration of Action
Cartinex reaches peak blood levels within 2-5 hours after administration. The anti-anginal effects develop gradually over the first week of treatment, with maximum benefits typically seen after 2-4 weeks of consistent use. Effects last approximately 12 hours per dose.
Side Effects
Common side effects include dizziness, headache, constipation, and nausea. Some patients experience fatigue, peripheral edema, or abdominal pain. Serious but rare side effects include QT prolongation, kidney problems, or severe allergic reactions requiring immediate medical attention.
Warning
Cartinex may cause QT interval prolongation, potentially leading to serious cardiac arrhythmias. Avoid in patients with existing QT prolongation, severe kidney or liver disease. Do not use for acute angina attacks. Monitor kidney function and electrolytes during treatment, especially in elderly patients.
Pregnancy and Breastfeeding
Cartinex should only be used during pregnancy if potential benefits justify potential risks to the fetus. Limited data exists regarding safety in pregnancy. It’s unknown if Ranolazine passes into breast milk. Consult healthcare provider before use during breastfeeding.
Interaction
- May increase levels of simvastatin and other statins
- Potential interaction with digoxin, requiring monitoring
- May be affected by strong CYP3A inhibitors like ketoconazole
- Possible interaction with certain antiarrhythmics
- May alter effectiveness of some diabetes medications
- Grapefruit juice may increase Ranolazine levels
Precaution
Use with caution in patients with kidney or liver impairment, elderly patients, or those with electrolyte imbalances. Monitor for signs of kidney dysfunction. Avoid sudden discontinuation. Inform all healthcare providers about Cartinex use before any medical procedures or starting new medications.
Important Information
Cartinex is not for treating acute angina attacks; use sublingual nitroglycerin for immediate relief. Continue all other prescribed cardiac medications unless instructed otherwise. Store at room temperature in original container. Report any unusual symptoms or side effects to your healthcare provider promptly. Regular follow-up appointments are essential for monitoring treatment effectiveness and safety.
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Customer questions & answers
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I was asked to use just one sachets out of the e sachets in the pack
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Q I was asked to use just one sachets out of the e sachets in the pack answer nowAsked by Mariam on May 13, 2025 9:05 pmA
Hello Mariam,
If your doctor instructed you to use only one sachet from the pack of Cartinex 500mg (Ranolazine), it's important to follow that guidance. Cartinex is typically prescribed for chronic angina, and the standard dosage is 500mg twice daily. However, dosages can vary based on individual health conditions and responses to the medication. If you have any uncertainties or concerns about your prescribed dosage, please consult your healthcare provider for clarification.
Can I take cartinex and nebilong H together
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Q Can I take cartinex and nebilong H together answer nowAsked by Tunmise on November 28, 2024 10:13 amA
Hello Tunmise,
Cartinex 500mg (Ranolazine) and Nebilong H (Nebivolol 5mg + Hydrochlorothiazide 12.5mg) can be taken together, but only under the guidance of a healthcare professional.
These medications work differently:
- Cartinex helps manage chronic angina (chest pain).
- Nebilong H controls high blood pressure and heart rate.
Taking them together may increase the risk of side effects like dizziness or low blood pressure. Please consult your doctor to ensure safety and proper dosage.
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