Cetroxol Suspension Powder (Azithromycin) is a highly effective antibiotic medication that belongs to the macrolide class. It is formulated as a powder that can be reconstituted into an oral suspension, making it a convenient and easy-to-administer option, especially for pediatric patients. This innovative formulation ensures accurate dosing and improves patient compliance, contributing to successful treatment outcomes.
Uses
Cetroxol Syrup is a broad-spectrum antibiotic indicated for treating various bacterial infections, including:
- Respiratory tract infections (bronchitis, pneumonia)
- Ear infections (otitis media)
- Skin and soft tissue infections
- Typhoid Fever
- Throat infections
- Sexually transmitted infections (non-gonococcal urethritis, mycoplasma, chlamydia infections and cervicitis)
It is particularly effective against susceptible strains of bacteria, such as Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
Benefits
- Broad-spectrum antibiotic coverage for common pediatric infections
- Convenient once-daily dosing improves compliance
- Shorter treatment courses compared to other antibiotics
- Pleasant taste formulation for children
- Effective against atypical bacterial pathogens
- Reduced gastrointestinal side effects compared to other macrolides
- Available in age-appropriate dosing
- Good tissue penetration for effective treatment
- Stable suspension once reconstituted
How It Works
Cetroxol inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing bacteria from producing essential proteins needed for growth and reproduction. This bacteriostatic action stops bacterial multiplication, allowing the immune system to eliminate the infection effectively.
Dosage
| Age Group | Daily Dosage | Treatment Duration |
|---|---|---|
| 1-11 months | 1 sachet once daily | 3-5 days |
| 1-2 years | 1.5 sachets once daily | 3-5 days |
| 3-5 years | 2 sachets once daily | 3-5 days |
| 6-12 years | 3 sachets once daily | 3-5 days |
| 13-18 years | 4 sachets once daily | 3-5 days |
Mix powder with clean water as directed. Give at same time daily, preferably on empty stomach or 2 hours after meals.
Duration of Action
Cetroxol begins working within 2-4 hours of administration with peak concentrations reached in 2-3 hours. The antibiotic remains active in tissues for several days due to its long half-life, allowing once-daily dosing and shorter treatment courses.
Side Effects
Common side effects include mild diarrhea, nausea, stomach pain, and vomiting. Some children may experience headache, dizziness, or temporary changes in taste. Serious allergic reactions are rare but require immediate medical attention including rash, difficulty breathing, or swelling.
Warning
Complete the full prescribed course even if symptoms improve. Cetroxol may cause rare but serious heart rhythm abnormalities. Discontinue and seek medical help for persistent vomiting, severe diarrhea, skin rash, or signs of liver problems including yellowing of skin or eyes.
Pregnancy and Breastfeeding
Cetroxol is generally safe during pregnancy when needed for bacterial infections. It passes into breast milk in small amounts but is considered compatible with breastfeeding. Consult healthcare provider for specific guidance during pregnancy or nursing.
Interaction
- May increase levels of certain blood thinners requiring monitoring
- Potential interaction with some seizure medications
- May affect absorption of certain vitamins and minerals
- Possible reduced effectiveness of oral contraceptives in adolescents
- May interact with antacids if given simultaneously
Precaution
Use with caution in children with liver or kidney problems, heart conditions, or previous allergic reactions to macrolide antibiotics. Store reconstituted suspension in refrigerator and use within 10 days. Shake well before each dose. Ensure adequate hydration during treatment.
Important Information
Cetroxol treats only bacterial infections, not viral infections like common cold or flu. Misuse of antibiotics can lead to resistant bacteria. Store powder sachets at room temperature in dry place. Once mixed, refrigerate and discard after 10 days. Contact healthcare provider if symptoms worsen or new symptoms develop during treatment.
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